关键词: 毛细血管瘤, 视盘, 激光治疗, Von Hippel-Lindau病

Abstract:

Objective To observe the clinical efficacy of laser therapy to juxtapapillary capillary hemangioma. Design Retrospective case series. Participants 11 patients（12 eyes）with juxtapapillary capillary hemangioma were reviewed. Methods All patients were treated with single or combined laser therapy, among which traditional laser therapy (532 nm green laser or 577 nm yellow laser) for 5 eyes, photodynamic therapy (PDT) for 4 eyes, PDT combined with traditional laser therapy for 3 eyes. Treatment times were 1 to 7 times, with a mean of （3.3±2.1） times; The follow-up period ranged from 2 months to 132 months, with a mean of （42.5±41.8）months. Visual acuity, tumor change, subretinal fluid, hemorrhage and epiretinal membrane were observed and analysis before and after treatment. Main Outcome Measures Vision, tumor change, subretinal fluid, hemorrhage and epiretinal membrane before and after treatment. Results The visual acuity before treatment ranged from CF/30 cm to 1.0, in which ≥0.5 in 3 eyes, <0.5 and ≥0.1 in 5 eyes, <0.1 in 4 eyes. The visual acuity after treatment ranged from hand motion (HM) to 1.0, in which ≥0.5 in 1 eye, <0.5 and ≥0.1 in 7 eyes, <0.1 in 4 eyes. Tumor regressed in 8 eyes, remained no change in 1 eye and became larger in 3 eyes. Subretinal fluid reduced or disappeared in 8 eyes, enlarged in 3 eyes. 5 eyes developed secondary epiretinal membrane, and 4 eyes developed secondary pigmentation in macula. Conclusion Timely treatment with single or combined laser therapy can help to control tumor growth of juxtapapillary capillary hemangioma in a certain extent.

Key words: capillary hemangioma, optic disk, laser therapy, Von Hippel-Lindau disease