Abstract:

Objective To study imaging findings for retinoblastoma patients with distant metastasis. Design Retrospective case series. Participants 14 retinoblastoma patients with distant metastasis. Methods The image of 14 retinoblastoma patients with distant metastasis were analyzed retrospectively. The magnetic resonance imaging(MRI) features analyzed included lesion location, morphology, scope and the characteristics of contrast. Main Outcome Measures MRI and computed tomography (CT) findings. Results 11 cases developed direct extension. Metastatic lesions were found in central nervous system in 9 patients, in bone in 3 patients, in neck lymph nodes in 3 patients. The central nervous system was the most common involved organ. Conclusion MRI and CT could find metastatic tumor of retinoblastoma, which were very useful for guiding clinical treatment. (Ophthalmol CHN, 2015, 24: 301-303)

Key words: retinoblastoma, direct extension and distant metastasis, imaging findings