Abstract:

With the focus on the role of preservative in eye drops, preservative-free eye drops came into being. At present, there is no preservative in eye drops following the improvement of the packaging bottle. From a single dose to a multi dose packaging bottle, each has its advantages and disadvantages. Single dose packaging bottle is convenient to carry and can basically avoid microbial contamination because of the short exposure time. But the production cost is high and can lead to the waste of eye drops. Multi-dose packaging bottle can achieve preservatives-free, and can be used repeatedly. But patients need to change using habits. It needs certain viscosity of eye drops, and the ratio of bottle production cost increases. With the deeper study, eye drop bottles should be designed to be more safe, convenient, cost-effective and dose-controllable.

Key words: eye drops, preservatives-free, packaging bottle