Ophthalmology in China

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Effect of orthokeratology lenses, peripheral defocus spectacle lenses, single vision spectacles of optic correction on myopia control

GUO Yin1,2, LIU Li-juan2, GUO Xi3, ZHANG Rong1, LIU Yu-cheng1, XIE Xiao-fang4, TANG Ping1, LV Yan-yun1, XIE Pei-ying3, GUO Xiu-hua5, XU Liang2   

  1. 1. Tongren Eye Care Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; 2. Beijing Institute of Ophthalmology; Beijing Key Lab. of Ophthalmology and Visual Science; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100005, China; 3. Beijing Beiyi Optometry & Ophthalmology Center, Beijing 100027, China; 4. Beijing Zhiliang Optometry Technology Ltd. Corporation, Beijing 100062, China; 5. Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China
  • Received:2015-03-23 Online:2016-09-25 Published:2016-09-26
  • Contact: XU Liang, Email: xlbio1@163.com; GUO Xiu-hua, Email: guoxiuh@ccmu.edu.cn

Abstract:

Objective To assess the effect of myopia control with single vision spectacle lenses(SV), orthokeratology lenses(OK), and peripheral defocus spectacle lenses(PD). Design Prospective, non-randomized case control study. Participant Three hundred and twenty one children were enrolled in the study from Beijing Institute of Ophthalmology, Tongren Eye Care Center and Beijing Beiyi Optometry & Ophthalmology Center. 141 children (43.9%, 141/321) completed the follow up, with a mean age of 11.41±2.29 years. Methods All children received a comprehensive examination, including visual acuity, cycloplegia refraction, slit lamp, Lenstar ocular biometry, color fundus photographs and were followed up one year later. Parents selected the types of correction on their own. Main Outcome Measures Change of refraction, axial length and parapapillary atrophy before and after wearing. Results The mean equivalent spherical(SE) and axial length(AL) of 141 children at baseline were -2.89±1.34 D and 24.92±0.34 mm, respectively. At one-year follow-up visit, elongation of AL in children with OK was 0.13±0.16 mm, significantly less than the other two groups (F=48.820, P<0.001). Progression of myopia was -0.77±0.79 D and -0.94±0.47 D in SV group and PD group respectively. There was no significant difference between groups (t=1.080, P=0.283). Presence of enlargement of parapapillary atrophy in OK group was 15.0%, significantly lower than SV group (66.7%) and PD group (38.6%). Conclusions Compared to single vision spectacle lenses and peripheral defocus spectacle lenses, orthokeratology is most effective for myopia control. (Ophthalmol CHN, 2016, 25: 302-306)

Key words: myopia control, orthokeratology lenses, single vision spectacle lenses, peripheral defocus spectacle lenses