Abstract:

Objective To measure the normal retinal oxygen saturation (SaO2) values with retinal oximetry in healthy Chinese population. Design Observational cross-sectional study. Participants The study included 91 normal healthy subjects (mean age: 37.5±14.0 years；Male：37，Female：54). Method Healthy Chinese volunteers underwent systematic and ophthalmic examinations. Retinal oxygen saturation was examined by a noninvasive retinal oximeter. Main Outcome Measures The mean retinal arterial oxygen saturation (SaO2-A); the mean retinal venous oxygen saturation (SaO2-V); the mean retinal arteriovenous difference in oxygen saturation (SaO2-AV). Results The mean SaO2-A was 92.1±7.2%; the mean SaO2-V was 52.5±6.6%; the mean SaO2-AV was 39.6±7.5%. The mean SaO2-A(98.5±10.1%), SaO2-V(57.3±8.7%) and SaO2-AV(41.3±11.9%) were significantly higher in the superior nasal quadrant. Age was associated with increased SaO2-A (B=0.24, P=0.049) and SaO2-AV (B=0.219, P=0.046). Smoking was associated with decreased SaO2-V (B=-0.25, P=0.033). Hyperlipidemia was associated with increased SaO2-A (B=0.26, P=0.018). Male was associated with an increase in SaO2-AV(B=-0.253, P=0.019). Conclusions Aging may increase SaO2-A and SaO2-AV, whereas smoking may cause decreased SaO2-V. Male are likely to have higher SaO2-AV. （Ophthalmol CHN, 2016, 25： 339－342）

Key words: retinal oxygen saturation, retinal oximetry