Ophthalmology in China

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Therapeutic plasma exchange for acute optic neuritis 

ZHUANG Yuan1, XU Quan-gang2, WEI Shi-hui2.   

  1. 1. Department of Transfusion, General Hospital of PLA, Beijing 100853, China; 2. Department of Ophthalmology, General Hospital of PLA, Beijing 100853, China
  • Received:2016-10-26 Online:2017-01-25 Published:2017-01-20
  • Contact: XU Quan-gang, Email: xuquangang@126.com

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Abstract:

Therapeutic plasma exchange (TPE) can remove the pathogenic components effectively such as autoimmune antibodies and proinflammatory cytokines in serum. It may also modify the immune function of patients. If patients with acute optic neuritis (ON) do not respond to intravenous methylprednisolone (IVMP) therapy or they are intolerant to IVMP, TPE may be beneficial in the acute setting. However, adverse events such as allergy and electrolyte disturbances should be alerted. The exact effect of TPE for acute ON and its optimal treatment strategy need to be further investigated. (Ophthalmol CHN, 2017, 26: 6-9)

Key words:  optic neuritis, therapeutic plasma exchange