Abstract:

Objective To determine the change of refractive power caused by treatment in patients with macular edema induced by retinal vein occlusion. Design Retrospective case series. Participants Forty six eyes of 46 consecutive patients with clinically significant macular edema with retinal vein occlusion. The subjects were divided into two groups: macular edema without macular detachment group and macular edema with macular detachment group. Methods All patients received intravitreal anti-vascular endothelial growth factor (VEGF) or posterior Tenon subtenon injection of triamcinolone (TA). The change in refraction (spherical equivalent refraction, SE) between baseline and the final visit without macular edema or the central subfield thickness (CST) measured by optical coherence tomography reached the thinnest level was analyzed in the two groups respectively. Main Outcome Measures SE. Results In macular edema without macular detachment group, the baseline SE, final visit SE and the mean absolute value of SE change was 0.38±1.71 D , 0.32±1.68 D , 0.31±0.32 D, respectively (t=0.577, P=0.571). In macular edema with macular detachment group, the baseline SE, final visit SE and the mean absolute value of SE change was 0.79±1.25 D, 0.26±1.15 D , 0.88±0.81 D, respectively (t=2.541, P=0.017). Conclusions Appropriate spectacle correction can be prescribed to patients with macular edema but without macular detachment any time during ongoing therapy using intravitreal anti-VEGF or posterior Tenon subtenon injection of TA. (Ophthalmol CHN, 2017, 26: 39-43)

Key words:  refractive change, macular edema, retinal vein occlusion