Abstract:

Objective To study the surgical approach and long-term outcome of local resection for the uveal neurogenic tumor. Design Retrospective case series. Participants 15 cases with uveal neurogenic tumor which got local resection in Beijing Tongren Eye Center from 1999 to 2011. Methods Record and analyze the patients' preoperative clinical characteristics, surgical approaches, postoperative outcomes and histological pathology. Main Outcome Measures Preoperative best corrected visual acuity（BCVA), location and size of tumor, postoperative BCVA, postoperative complications. Results The locations of the tumor were in ciliary body (7 cases, 46.7%), ciliochoroid (2 cases, 13.3%), and choroid (6 cases, 40%). The pathologic examination showed that 10 were schwannoma, 4 were glioneuroma and 1 was neurofibromatosis.  If tumor only involved choroid (6 cases), endoresection was carried out. If tumor involved ciliary body (9 cases), exoresection combined with vitrectomy was carried out. Patients were followed from 1 to 9 years. Nine patients(60%) BCVAs were equal to or better than preoperative. The leading causes of visual acuity decreasing.are retinal detachment and proliferative vitreoretinopathy. There was no local recurrence in all the 15 patients. One eye (6.7%) was enucleated because of neovascularization glaucoma. Conclusion Endoresection or endoresection combined with exoresection was an effective means to remove tumor intactly, conserve vision in eyes with uveal neurogenic tumors and minimize the risk of tumor iatrogenic dissemination.

Key words: uveal tumor, neurogenic tumor, surgical procedure