Abstract:

Objective To evaluate the efficacy and safty of microcatheter-assisted trabeculotomy for the childhood glaucoma with or without previous surgeries. Design Retrospective case series. Participants 28 cases (39 eyes) of children with primary congenital glaucoma (PCG) were treated with microcatheter-assisted trabeculotomy at Zhengzhou Second People's Hospital from April 2017 to May 2018. Methods 28 cases (39 eyes) were divided into two groups according to the surgery history. Group A (15 cases, 22 eyes) had no previous anterior chamber angle surgery. Group B (13 cases, 17 eyes) had one or more previous failed angle surgeries. The intraocular pressure(IOP), the number of the drugs for reducing intraocular pressure, and postoperative complications in two groups were observed. Main Outcome Measures IOP, number of drugs for reducing intraocular pressure, surgical success rate. Results Mean IOP decreased from (31.23±6.05) mmHg on 3 (median, range: 1~4) medications in Group A and (29.47±5.75) mmHg on 3 (median, range: 1~4) medications in Group B preoperatively to (15.14±4.63) mmHg on 0 (median, range: 0~2) medications in Group A and (15.65±4.03) mmHg on 0 (median, range: 0~2) medications in Group B at  last  visit  respectively (all P<0.05).  Complete success rate (77.27% vs 88.24%, P>0.05) were comparable between Group A (90.91%) and Group B (94.12%). Complications were minimal. Conclusion The result of 6 months or over shows that microcatheter-assisted trabeculotomy is effective and safe in the treatment of PCG for those children who have no previous angle surgery or those children who had one or more previous failed angle surgeries.

Key words: glaucoma, trabeculotomy, child