Abstract: Objective To observe the efficacy of modified meibomian gland tube acupuncture dredging method for early acute meibomian adenoiditis. Design Prospective comparative case series. Participants 105 patients with early acute syringopsitis in Second Hospital affiliated to Fujian Medical University from March 2015 to August 2017. Methods Patients were randomly divided into treatment group (56 cases) and control group (49 cases). Patients were also divided into severe and mild subgroup according to the severity of symptoms and degree of diffusion. There were 31 severe cases and 25 mild cases in treatment group, and 28 severe cases and 21 mild cases in control group. The treatment group was treated with modified meibomian gland tube acupuncture dredging method. The control group was treated with conventional conservative method. The mean follow-up time was（6.50±3.84） days. Main Outcome Measures Cure rate. Results The total cure rate in treatment group was 92.86%, significantly higher than that of control group (67.35%) (P=0.000). In mild patients, the cure rate of treatment group (96.00%) was higher than that of control group (80.95%) (P=0.04). In severe patients, the cure rate of treatment group (90.32%) was higher than that of control group (57.14%) (P=0.000). The duration of disease in treatment group was（5.0±2.98）days and (8.4±3.86）days in control group. The surgical rates（4.00% , 9.68% of mild and severe patients） in treatment group were lower than those of the control group (23.81%, 42.86% of mild and severe patients）(all P<0.05). Conclusions The modified meibomian gland tube acupuncture dredging method can effectively dredge meibomian gland tube in early acute meibomian adenoiditis, and shorten the course of disease, decrease the surgical rate. （Ophthalmol CHN， 2020, 29： 153-157）

Key words: meibomian adenoiditis, modified acupuncture dredging method