Ophthalmology in China

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Analysis on incidence of primary ocular malignant tumor in Beijing household registration according to database of World Health Organization's Cancer Incidence in Five Continents

Zhou Jichao, Wang Wei, Zhang Chun, Tian Yanjie, Zhao Suyan, You Debo   

  1. Department of Ophthalmology, Peking University Third Hospital, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing 100191, China
  • Received:2019-01-20 Online:2020-05-25 Published:2020-06-05
  • Contact: You Debo, Email: youdebo@yahoo.com E-mail:youdebo@yahoo.com
  • Supported by:
    National Natural Science Foundation of China (81670851)

Abstract: Objective To analyze the incidence characteristics of primary ocular malignant tumor in Beijing household registration according to database of World Health Organization's Cancer Incidence in Five Continents (CI5). Design Cross-sectional study. Participants Cancer registration data of Beijing registered population from January 1, 2003 to December 31, 2012 published by the World Health Organization's CI5 database. Methods Using the database information, combined with each annual demographic data provided by the Beijing Municipal Public Security Bureau, Beijing residents primary ocular tumor incidence and world standard demographic standardized incidence were calculated. The sites and pathological subtypes were analyzed. Main Outcome Measures Incidnece and standardized incidence of world standard population composition. Results According to the database, in the past 10 years, 740 patients with primary ocular malignant tumors were diagnosed in Beijing, with a population incidence of 6.11/million, the average age is 56.5 ± 17.6 years old, from 6 months old to 96 years old. Male/female is 1.2:1. The main pathological types were basal cell carcinoma (27.3%), followed by adenocarcinoma, sarcoma, retinoblastoma, and malignant melanoma, accounting for 13.2%, 11.8%, 10.9%, and 8.8%, respectively. Eyelid is the leading attacked site (68.3%), followed by eyeballs (18.3%) and orbits (4.8%). Within 10 years, no matter male or female, the incidence of ocular malignant tumors in different age groups was not statistically significant (all P>0.05). Conclusion According to the database, the incidence of primary ocular malignant tumor in Beijing residents registered in CI5 is 6.11/million, and the average age is 56.5±17.6 years. The top pathological types are basal cell carcinoma, followed by sebaceous gland carcinoma, sarcoma, retinoblastoma and malignant melanoma. Eyelid is the leading attacked site.

Key words: ocular malignant tumor, incidence, Beijing