Ophthalmology in China ›› 2021, Vol. 30 ›› Issue (2): 108-111.doi: 10.13281/j.cnki.issn.1004-4469.2021.02.006

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Clinic feature of eyelid granulomatous mass following forehead and face augmentation surgery

Yang Mingming1, Yang Bentao2, Jiang Libin1   

  1. 1Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Key Laboratory of  Ophthalmology and Visual Sciences, Beijing 100730, China； 2Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China

  • Received:2020-09-07 Online:2021-03-25 Published:2021-03-26
  • Contact: Jiang Libin, Email: jlbjlb@sina.com
  • Supported by:
    National Natural Science Foundation of China (81570836); Capital Development Foundation（2020-2-1082）

Abstract:  Objective To summary the clinic feature and treatment of eyelid granulomatous mass following forehead and face augmentation surgery. Design Retrospective case series. Participants 16 patients (22 eyes) with periorbital lumps following forehead and face augmentation surgery from 2019 to 2020 in Beijing Tongren Hospital. Methods Clinical manifestation, physical signs, ophthalmic imaging and treatment were reviewed. Main Outcome Measures Manifestation, neuroimaging features and outcome. Results All patients were female. Age ranged from 26 to 46 years with an average of 36.43 ±5.65 years old. 3 patients(18.7%) merely received facial creotoxin or hyaluronic acid injection. 13(81.2%) patients received facial fat injection with 1 patient among them received forehead creotoxin injection, and 4 of them received double eyelid surgery after facial fat injection. The average duration between last surgery and onset of symptom was 19.50±19.70 months, with a median of 12 months. 6(37.5%) of them had bilateral lumps and 10 (62.5%) had unilateral lumps. 2 (12.5%) of them had eyelid swelling. Lumps located in upper eyelid in 13 cases (81.2%), and located in lower eyelid in 2 patients(12.5%). Lumps located both upper and lower eyelid in1 patient(6.3%). All the patients were found the lumps unintentionally. MRI demonstrated a mass with hypointense or hyperintense signal (12 patients with 14 eyes) in T1WI and hyperintense signal (12 patients with 17 eyes) in T2WI. Contrast-enhanced MRI showed heterogeneous enhancement. All 16 following patients rejected to receive any treatment and their lumps showed no change during 6 mouths follow up. Conclusion As a rare complication, the clinic manifestation of eyelid granulomatous mass following forehead and face plastic surgery remain quite stable and have a high chance to be misdiagnosed. Radiologic feature combined with the history of facial augmentation surgery would be helpful for diagnosis.  (Ophthalmol CHN, 2021, 30: 108-111)


Key words: eyelid granulomatous mass, facial augmentation surgery