Ophthalmology in China ›› 2022, Vol. 31 ›› Issue (4): 245-252.doi: 10.13281/j.cnki.issn.1004-4469.2022.04.001

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Extracellular deposits associated with age-related maculopathy： Baseal linear daposit and drusen

Huang Houbin   

  1. Senior Department of Ophthalmology, PLA General Hospital, Beijing 100853, China; Department of Ophthalmology, Hainan Hospital of PLA General Hospital, Sanya 572013, China; The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510280, China
  • Received:2022-05-10 Online:2022-07-25 Published:2022-07-29
  • Supported by:
    High and New Technology Project of Hainan Key Research and Development Plan (ZDYF2020031); Special Scientific Research Project of the Logistic Support Department of the Chinese Military Committee(19BJZ39)

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Abstract:  With ageing, many deposits predominantly lipoprotein-derived debris accumulated outside RPE result in various lesions. The deposits between the basal lamina of basement membrane of RPE and the inner collagenous layer of Bruch's membrane form gradually lipid wall, basal linear deposit, hard drusen and soft drusen. Cuticular drusen and pachy drusen are variations of hard drusen. All of the above deposits which can be recognized clinically to a variable extent are associated with age-related macular degeneration and of high significance. (Ophthalmol CHN, 2022, 31: 245-252)


Key words:  age-related macular degeneration, druse, basal linear deposit