Ophthalmology in China ›› 2026, Vol. 35 ›› Issue (2): 81-91.doi: 10.13281/j.cnki.issn.1004-4469.2026.02.001

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Macular pigments

Huang Houbin   

  1. Senior Department of Ophthalmology, Chinese PLA General Hospital, Beijing 100853, China; Department of Ophthalmology, Hainan Hospital of PLA General Hospital, Sanya Hainan 572013, China
  • Received:2025-11-01 Online:2026-03-25 Published:2026-03-25
  • Contact: Huang Houbin,Email: 536273642@qq.com
  • Supported by:
    High and New Technology Project of Hainan Key Research and Development Plan (ZDYF2024GXJS032); Health Care Special Project of PLA Logistics Research Fund (23BJZ37); Scientific Research Project of Health Industry in Hainan Province (22A200351)

Abstract: Macular pigments refers to lutein, zeaxanthin, and meso-zeaxanthin that are concentrated in macula lutea. They all belong to xanthophyll which is a subclass of carotenoid. These pigments are closely associated with eye diseases, particularly age-related macular degeneration, as well as fundus imaging. Currently, it is widely believed that dietary intake or supplementation of these three xanthophylls may benefit eye health and visual function. This article systematically sorts out the sources, chemical structures, distribution within the body, transport and uptake mechanisms, spectral characteristics, clinical detection methods, functions, and clinical significance of macular pigment, aiming to raise attention to macular pigment and related researches.

Key words:  Macular pigment, Fundus imaging, Medicated diet, Eye health