Abstract: There are six main classifications and thousands of all combination schemes of topical intraocular pressure-lowering agents currently available in management of glaucoma. The clinical guidelines have kept renewing in recent years aiming to guide the clinical doctors in their maximum reasonable medical therapy. In the present paper, the selection path of drug application and the expert consensus from 2011 World Glaucoma Congress are briefly introduced, with the target intraocular pressure and the first-line medications as a center. (Ophthalmol CHN, 2012, 21: 11-13)

Key words: glaucoma/medical therapy, expert consensus, first-line medication