Abstract: Objective To analyze the clinical effects on binocular vision after LASIK for myopic anisometropia, and evaluate its clinical value in the view of vision quality. Design Prospective case series. Participants 36 cases (72 eyes) with myopic anisometropia who received LASIK. Methods All the cases were followed-up for at least 3 months. The uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), refraction and binocular vision were analyzed before and 3 months after surgery. Main Outcome Measures UCVA, BCVA, refraction，simultaneous binocular visions，combined, short and long distance stereopsis visions before and after LASIK. Results The UCVA was 0.01~0.2 before LASIK, while the UCVA reached 1.0 after LASIK. The amount of myopic anisometropia before LASIK was (5.01±1.96) D（ 2.50~9.00 D）, and the amount was (0.28±0.22) D（0.00~0.75 D） after LASIK（P＜0.01）. In 26 cases with high degree anisometropia (2.50 D≤anisometropia degree≤6.00 D), 12 cases of glasses-corrected patients got normal short distance stereopsis vision and 22 cases of LASIK-treated patients got normal short distance stereopsis vision (P＜0.05); in the 10 cases with severe anisometropia (anisometropia degree ＞6.00 D), there was no patients who got normal short distance stereopsis vision at both the pre-operation and post-operation. 33 cases of glasses-corrected patients and 34 cases of LASIK-treated patients got simultaneous binocular visions (P>0.05). 18 cases of glasses-corrected patients and 33 cases of LASIK-treated patients got combined visions. 13 cases of glasses-corrected patients and 23 cases of LASIK-treated patients got long distance stereopsis visions (P<0.05). There was no significant difference in simultaneous binocular visions, but of great significance among combined, and long distance stereopsis visions (P＜0.05). Conclusions LASIK for myopic anisometropia can improve the visual acuity, reduce the refractive difference, and increase combined and stereopsis vision. LASIK was effective for myopic anisometropia.

Key words: LASIK, anisometropia, myopia, binocular vision