Abstract: 【Abstract】 Objective To evaluate the short-term change of intraocular pressure (IOP) after vitrectomy combined with phacoemulsification and intraocular lens (IOL) implantation. Design Retrospective comparative cases series. Participants 106 eyes of 102 consecutive inpatients who had undergone vitrectomy in Department of Ophthalmology, Beijing Tongren Hospital  in 2010. Methods The cases with vitreous hemorrhage/opacity or macular disease who had undergone standard 20 gauge pars plana vitrectomy combined with phacoemulsification and intraocular lens implantation (32 eyes of 30 patients) or without (74 eyes of 70 patients), excluding the cases with preoperative medical history of any possible effects on IOP. Main Outcome Measures IOP. Results Compared the combined cataract operation group with single vitrectomy group, the preoperative IOP (13.8±3.9, 14.5±3.0 mm Hg) had no significant difference (P=0.319), the average IOP of postoperative day 1 (16.4±9.1, 16.4±9.1 mm Hg), day 2 (13.9±5.6, 14.7±5.1 mm Hg) and day 3 (13.1±4.4, 13.8±4.6 mm Hg) had no significant difference (P>0.05 for each). Average IOP of postoperative day 1 was significantly higher than the preoperative one in the single vitrectomy group. Postoperative ocular hypertension incidence (15.6% vs 27.1%) in the two groups had no significant difference, which both mainly (80% vs 90%) occurred on the first postoperative day. All the five cases with ocular hypertension in the combined group occurred in eyes with diabetic retinopathy. Conclusion Combined with cataract surgery does not significantly increase the recent IOP and the incidence of ocular hypertension after vitrectomy. (Ophthalmol CHN, 2012, 21: 264-267)

Key words: vitrectomy, cataract extraction, intraocular pressure