Abstract: The tight anatomic relationship between sella region and visual pathway makes the ocular findings caused by lesions in sella region pretty common clinically, some of which are hard to distinguished with the features of some conditions traditionally considered as primary eye diseases. Different types of visual field defects such as bi-temporal hemianopia, vision loss and optic nerve atrophy are common findings due to optic chiasm lesions caused by sella region mass. In addition to ocular findings, getting familiar with the systemic symptoms and sign of different kind of sella region tumors are helpful to early diagnosis and treatment. Optic neuropathy can be similar with glaucomatous optic neuropathy in some conditions. Should we distinguish them mainly based on typically clinical features or routinely perform image study for the patients diagnosed as normal tension glaucoma? The empty sella found by brain MRI can co-exist with some ocular findings, but these two findings can both be the result of long-existing intracranial hypertension, instead of one can cause the other. The controversies about the relationship between sella region lesions and ocular finding require us take a comprehensive way considering the aspects of research, clinical practice, medical ethic and economics to provide a good diagnostic and treatment stratagem for benefiting the patients most. (Ophthalmol CHN, 2012, 21: 289-291)

Key words: space-occupy lesion of sella region, empty sella, optic nerve , glaucoma