Abstract: With the developments in the fields of medicine and biomedicine, physicians are not only required to have a high level of clinical skills,  but more emphased to have understanding, analysis, synthesis, inferring and practicing abilities to adapt to the needs of modern medicine. The modern evidence-based practice emphasizes the "student-based, problem-based" educational model. Raising clinical questions using the PICOT (population, intervention, comparator, outcome, time) principle is extremely important for the medical graduates in their clinical practice training, especially for the retinal graduate students. Utilizing the evidence-based medicine resources as much as they can, practicing actively, cultivating the science of clinical thinking are all necessary. Cultivating the evidence-based thinking mode has special significance for those who want to be an excellent retinal specialist. (Ophthalmol CHN, 2012, 21: 357-359)

Key words: evidence-based medicine, postgraduate medical education, thinking mode of evidence-based medicine