Abstract:  Objective To evaluate intra-session repeatability of objective optical quality parameters measured by the Optical Quality Analysis System (OQAS). Design Evaluation of diagnostic technology. Participants Twenty-six Chinese healthy adults (48 eyes) aged 18 to 41-years old (11 males and 15 females) were enrolled. Method Optical quality of each subject was evaluated by the OQAS with the pupil diameter of 4.0 mm. Ten consecutive measurements of the following parameters: the modulation transfer function cutoff frequency (MTFcutoff), the Strehl2D ratio, the OQAS values (OVs) at contrasts of 100%, 20%, 9% and the objective scatter index (OSI), were performed by one experienced examiner. The repeatability limit (RL) of each parameter was evaluated using SAS software. Main Outcome Measures The RLs of the six parameters of OQAS. Results The MTFcutoff , Strehl2D ratio, OV100%, OV20%, OV9% and OSI of the participants was 39.55±10.99, 0.23±0.07, 1.32±0.37, 1.36±0.46, 1.38±0.52, and 0.70±0.43, respectively. The RLs (percentage) of which were 17.74%, 24.95%, 17.74%, 20.59%, 23.31%, and 37.07%, respectively. Conclusion Measurements of objective optical quality provided by OQAS showed a good repeatability in normal subjects.

Key words: Optical Quality Analysis System, optical quality