Abstract: The quality of medical postgraduate training concerns the construction of high-level medical echelon. Modern medical graduate education emphasizes student-centered and problem-centered culture mode. In order to maximize the benefits of patients, problems derived from clinical practice need to get concise under the guidance of evidence-based medicine, and the best evidence related to diseases need to be integrated. In this manuscript, considering the status quo of the medical graduate training system, the main problems of the system were analysed. It would play positive roles in promoting modern medical graduate education that understanding the PICOT(P: population, I: intervention, C: comparator, O: outcome, T: time) principle and paying attention to the cultivation of clinical research ability. (Ophthalmol CHN, 2013, 22: 348-350)

Key words: PICOT principle, the medical graduate educational system, evidence-based medicine