The value of imaging in evaluating disease activity of thyroid associated ophthalmopathy

doi:10.13281/j.cnki.issn.1004-4469.2018.05.001

Abstract

Abstract:

Thyroid-associated ophthalmopathy (TAO) is an organ-specific autoimmune disease. Clinical activity score (CAS) is often used for the assessment of disease activity in TAO, but it has certain limitations. The morphology of extraocular muscles（orbital extraocular muscle coronal area/total orbit coronal area ratio，OM/TOA ratio）in compated tomography (CT) imaging were positively correlated with CAS. Quantitative analysis of T2 mapping magnetic resonance imaging (MRI) of extraocular muscle indicated that T2 value of extraocular muscle was closely related to the effect of immunosuppression, which was helpful for evaluating the effect of immunosuppression treatment. SPECT/CT using 99mTc-DTPA for the assessment of disease activity in TAO, which can obtain functional information and anatomical information in one imaging. It can be used as an effective complement to CAS. Modern medical imaging, especially functional imaging, has great application value in evaluating disease activity of TAO. （Ophthalmol CHN， 2018, 27： 321-324）

Key words: thyroid-associated ophthalmopathy；clinical activity score, computed tomography, magnetic resonance imaging

LI Mei1， YAN Fei2. The value of imaging in evaluating disease activity of thyroid associated ophthalmopathy[J]. Ophthalmology in China, doi: 10.13281/j.cnki.issn.1004-4469.2018.05.001.

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The value of imaging in evaluating disease activity of thyroid associated ophthalmopathy

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