Abstract: Objective To measure the amount of aged 7-14 years normal children’s tear secretion by 5 second tear secretion measurement method and study its application value. Design Diagnostic test. Participants 49 subjects of aged 7-14 years normal children from Beijing Aier-Intech Eye Hospital were included. Methods All subjects underwent 5-second tear secretion measurement and the data was analyzed statistically. The consistency of two measurement results were tested by Bland-Altman method. Main Outcome Measures The amount of tear secretion, Bland Altman 95% consistency limit, intraclass correlation coefficient (ICC). Results The mean value of 98 eyes was 3.71±2.36 mm. There was no significant difference between right and left eye groups (right eye 3.69±2.10 mm, left eye 3.73±1.98 mm), male and female groups (male 3.79±2.16 mm, female 3.55±2.06 mm), and different age groups(3.94±2.23 mm in 7-10 year old group, 3.31±1.73 mm in 11-14 years old group). The consistency of the two measurements are good. The mean value of right eye difference was -0.061, the 95% consistency limit of Bland Altman was -4.10~-3.98, and ICC was 0.763. Conclusions The 5-second tear secretion measurement method can quickly assess the amount of children's tear secretion function, which has high repeatability in children. (Ophthalmol CHN, 2022, 31: 301-304)

Key words:  , measurement of tear secretion, children