Evaluation of therapeutic efficiency of laser peripheral iridotomy with or without laser peripheral iridoplasty under the guidance of angle closure mechanisms in eyes with primary angle closure suspect

doi:10.13281/j.cnki.issn.1004-4469.2017.03.002

Ophthalmology in China

Previous Articles Next Articles

Evaluation of therapeutic efficiency of laser peripheral iridotomy with or without laser peripheral iridoplasty under the guidance of angle closure mechanisms in eyes with primary angle closure suspect

FAN Su-jie¹, LV Ai-guo¹, HAO Jie², LIANG Yuan-bo³, GUO Li-xia¹, LI Ai-lin¹, WANG Ning-li²

1. Department of Ophthalmology, Handan Eye Hospital, Hebei 056001, China; 2. Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; 3. The Affiliated Eye Hospital，School of Ophthalmology and Optometry, Wenzhou Medical University，Wenzhou 325027, China

Received:2016-12-03 Online:2017-05-25 Published:2017-06-02
Contact: WANG Ning-li, Email: wningli@vip.163.com E-mail:wningli@vip.163.com

Abstract

Abstract:

Objective To quantitatively measure the changes in anterior segment morphology by using ultrasound biomicroscopy (UBM) after laser peripheral iridotomy (LPI) with or without laser peripheral iridoplasty under the guidance of angle closure mechanisms in eyes with primary angle closure suspect (PACS). Design Prospective case series. Participants Sixty-five eyes in 50 PACS consecutive patients with PACS were enrolled from Jan. to Nov. 2016 in Handan Eye Hospital. Methods Each pre-operated eyes was evaluated by UBM according to the different mechanisms of angle closure. All selected patients were first treated with LPI. UBM examination were performed again 3 days after LPI. If there are still at least one quadrant angle contact closure, laser peripheral iridoplasty (LPIP) will be combined. Three days after LPLP, UBM was reviewed, and the therapeutic effects were evaluated according to the changes of UBM measurement parameters. Main Outcome Measures The parameters of anterior chamber angle in UBM images, including central anterior chamber depth (ACD), angle of anterior chamber opening distance(AOD), trabecular iris angle(TIA), angle crypt area(ARA)、trabecular ciliary body distance (TCPD)、iris thickness (IT). Results Forty-seven eyes were only treated by LPI, which showed pure pupillary block. AOD, TIA, ARA, TCPD were significantly widen after LPI than that at presentation in eyes (all P<0.01). IT were unchanged after LPI than that at presentation in eyes (P=0.465). Eighteen eyes were treated by LPI combined LPIP, which presented multiplemechanism, the AOD, TIA, ARA, TCPD were significantly widen after LPI+LPIP than that at presentation in eyes (all P<0.01). IT were thinner after LPIP than that at presentation and after LPI in eyes (P<0.01). Conclusion After LPI, UBM can be used to determine the mechanism of angle closure, and to consider whether combined LPIP, which can further improve the efficacy of multiplemechanism PACS.

Key words: primary angle closure suspect, ultrasound biomicroscopy, laser peripheral iridotomy, laser peripheral iridoplasty

FAN Su-jie1, LV Ai-guo1, HAO Jie2, LIANG Yuan-bo3, GUO Li-xia1, LI Ai-lin1, WANG Ning-li2. Evaluation of therapeutic efficiency of laser peripheral iridotomy with or without laser peripheral iridoplasty under the guidance of angle closure mechanisms in eyes with primary angle closure suspect[J]. Ophthalmology in China, doi: 10.13281/j.cnki.issn.1004-4469.2017.03.002.

[1]	Su Xinjie, Zhang Dawei, Li Shanshan, Dai Weijia. Correlations between chamber angle structures and dark room provocative test in shallow anterior chamber eyes [J]. Ophthalmology in China, 2024, 33(4): 267-274.
[2]	Wang Linhao, Wang Junming, Deng Chaohua. Comparison of iris and ciliary biometry parameters between eyes of primary angle closure glaucoma and primary angle closure suspects [J]. Ophthalmology in China, 2022, 31(1): 20-25.
[3]	Li Sizhen, Guo Chunyu, Liang Yuanbo, Fan Sujie, Cai Xiaogu, Sun Xia, Guo Lixia, Sun Lanping, SUCIJANTI, Han Wei, Wang Ningli . Five years’ results of LPI on acute primary angle closure glaucoma and PAS extent influence evaluation [J]. Ophthalmology in China, 2021, 30(1): 11-19.
[4]	Wang Bingsong, Jia Hongyan, Cao Kai, Liu Ziqing, Zhao Aiping, Wang Tao. Comparative analysis of angle morphology in different quadrants of primary angle closure suspect eyes [J]. Ophthalmology in China, 2020, 29(5): 361-364.
[5]	Yan Xiaowei, Tang Guangxian, Zhang Hengli, Li Fan, Ma Lihua, Geng Yulei. Observation of the evolution of filtration channels after CLASS with ultrasound biomicroscopy [J]. Ophthalmology in China, 2020, 29(4): 309-314.
[6]	LI Ai-lin1,2, GUO Li-xia2, LV Ai-guo2, CUI Hong-yu2, ZHANG Zhi-hong2, ZHANG Xin2, FAN Su-jie2.. The study on the characteristics of ciliary body in primary acute angle closure glaucoma [J]. Ophthalmology in China, 2019, 28(1): 29-33.
[7]	WANG Cong1, YOU Qi-sheng2, ZHOU Jun1, PANG Xiu-qin1, SHI Xiang-yu1, LIU Yi1.. Clinical characteristics of complicated traumatic cyclodialysis [J]. Ophthalmology in China, 2018, 27(4): 301-304.
[8]	LI Qi-yan, MOU Da-peng, LI Hang, QING Guo-ping.. Effect of argon laser peripheral iridoplasty on corneal endothelium in acute angle closure glaucoma [J]. Ophthalmology in China, 2018, 27(4): 291-295.
[9]	LV Ai-guo1, 2, MU Da-peng3, GUO Li-xia2, LIANG Yuan-bo4, LI Si-zhen5, CUI Hong-yu2, ZHANG Zhi-hong2, FAN Su-jie2. Long-term outcomes of ultrasound biomicroscopy in eyes with primary angle closure suspect after laser peripheral iridotomy: a five-year progression study [J]. Ophthalmology in China, 2016, 25(1): 23-29.
[10]	LI Si-Zhen, WANG Ning-Li, LIANG Yuan-Bo, FAN Su-Jie, SUN Lan-Ping, CUI Hong, LI Hui, Sucijanti . Comparison of the anterior chamber angle and related structures in fellow eyes of acute and chronic primary angle-closure glaucoma [J]. Ophthalmology in China, 2014, 23(1): 26-30.
[11]	MOU Da-Peng, Lin-Zhong, Wang-Ning-Li, Fan-Su-Jie, SUN Lan-Ping, Liang-Yuan-Bo. Long term outcomes of ultrasound biomicroscopy in eyes with primary angle closure suspect after laser peripheral iridotomy: one year results [J]. Ophthalmology in China, 2013, 22(4): 244-248.
[12]	ZHAO Xin, HAO Yun-he, ZHANG Xin-lei, ZHAI Jiang-he, TIAN Jing, HE Yan. The two years efficacy of early intervention by laser peripheral iridotomy on high-risk primary angle-closure glaucoma [J]. Ophthalmology in China, 2013, 22(3): 171-175.
[13]	GUO Chun-yu1, LI Si-zhen2, CAI Xiao-gu1, GUO Li-xia3, FAN Su-jie3, CUI Hong-yu3, ZHANG Zhi-hong3, ZHANG Qing1, SUN Lan-ping3, SUN Xia1, LIANG Yuan-bo4, WANG Ning-li1. . Comparison between the efficacy of laser peripheral iridotomy with and without laser peripheral iridoplasty in synechial angle closure: a 5-year follow-up study [J]. Ophthalmology in China, 2013, 22(1): 14-18.

Evaluation of therapeutic efficiency of laser peripheral iridotomy with or without laser peripheral iridoplasty under the guidance of angle closure mechanisms in eyes with primary angle closure suspect

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 13

Recommended Articles

Metrics

Comments