国际眼科纵览 ›› 2024, Vol. 48 ›› Issue (3): 210-216.doi: 10.3760/ cma.j.issn.1673-5803.2024.03.010

• 综述 • 上一篇    下一篇

白内障术后黄斑水肿的研究进展

胡宜卓 张凤妍   

  1. 郑州大学第一附属医院眼科,郑州 450052
  • 收稿日期:2023-10-30 出版日期:2024-06-22 发布日期:2024-06-17
  • 通讯作者: 张凤妍,Email: zhangfengyanx@aliyun.com E-mail:zhangfengyanx@aliyun.com

Research advance of peudophakic cystoid macular edema

Hu Yizhuo, Zhang Fengyan   

  1. Department of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
  • Received:2023-10-30 Online:2024-06-22 Published:2024-06-17
  • Contact: Zhang Fengyan, Email: zhangfengyanx@aliyun.com E-mail:zhangfengyanx@aliyun.com

摘要: 白内障术后黄斑水肿(pseudophakic cystoid macular edema,PCME)也称Irvine-Gass综合征,是白内障术后无法预测视力下降的常见原因。糖尿病、黄斑前膜、应用前列腺素类似物等为其危险因素。既往认为炎症是其主要的致病因素,近年研究发现很多细胞因子和免疫相关因子可能也参与了PCME形成。在治疗上除了常规的术后非甾体抗炎药和糖皮质激素点眼之外,还有一些新的防治方法,如术中前房应用去氧肾上腺素/酮咯酸合剂、Tenon囊下/结膜下注射糖皮质激素、玻璃体内注射曲安奈德或地塞米松玻璃体植入剂;术后泪小管地塞米松植入剂及微脉冲激光等。

关键词: 白内障, 黄斑水肿, Irvine-Gass综合征

Abstract: Pseudophakic cystoid macular edema (PCME), also known as Irvine-Gass syndrome, is the most common cause of unexpected visual loss after cataract surgery. Diabetes mellitus, epiretinal membrane, prostaglandin analogues are its risk factors. It’s widely accepted that inflammation is the leading pathological mechanism, some cytokines and immune-relatedfactors may contribute to the pathological process. As for the prophylactic and treatment, besides the conventional nonsteroidal anti-inflammatory drug (NSAID) and steroid, new researches indicate that intraoperative intracameral phenylephrine-ketorolac, subtenon/subconjunctival steroid, dexamethasone implant or triamcinolone acetonide, postoperative intracanalicular corticosteroids, yellow subthreshold micropulse laser achieve promising outcome.

Key words: cataract, macular edema, Irvine-Gass syndrome