关键词: 晶状体悬韧带, 超声生物显微镜, 扫频源前段相干光断层扫描仪, CASIA2, Pentacam

Abstract: The lens zonules play a crucial role in maintaining the normal position and shape of the lens. Laxity or rupture of the lens zonules can lead to adverse outcomes such as changes in anterior chamber depth,  increased intraocular pressure,  angle closure,  and partial dislocation of the lens. Abnormalities in lens zonule functionality are prevalent and often concealed in populations with high myopia and angle-closure glaucoma,  presenting significant challenges to cataract surgery. These abnormalities can lead to complications during surgery,  such as difficulty in capsulorhexis,  posterior capsule rupture,  and dropping of the lens into the vitreous cavity. Therefore,  preoperative assessment of lens zonule function is critically important. Currently,  clinical tools such as Ultrasound Biomicroscopy (UBM),  the new generation Swept-source anterior segment optical coherence tomography (SS-AS-OCT),  CASIA2,  and the Pentacam,  which is based on the principle of the Scheimpflug camera and analyzes the anterior segment in three dimensions,  are available for detecting and assessing the function of the lens zonules. UBM can directly detect ruptured lens zonules and assess the location of zonular ruptures but requires patient cooperation for eye movement during the examination. CASIA2,  a non-contact measurement device,  indirectly evaluates lens zonular function by measuring parameters such as anterior chamber depth,  anterior lens surface curvature radius,  lens thickness,  lens tilt,  and decentration,  but it cannot measure the posterior chamber and ciliary body morphology. Similar to CASIA2,  Pentacam assesses lens zonular function but has less comprehensive detection indicators and is prone to measurement errors influenced by factors such as ciliary body morphology. This article compares the advantages and disadvantages of these three instruments in assessing lens zonular function,  guiding clinicians to detect abnormalities in lens zonular function early,  particularly before cataract surgery,  thereby enhancing understanding of ocular pathologies.  (Int Rev Ophthalmol,  2025,  49:  8-12)

Key words: lens zonule, ultrasound biomicroscopy, swept-source anterior segment optical coherence tomography, CASIA2, Pentacam