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湿性年龄相关性黄斑变性的治疗现状

安喜艳  苏九妹   

  1.  300170 天津市第三中心医院眼科
  • 收稿日期:2015-02-12 出版日期:2015-08-22 发布日期:2015-09-07
  • 通讯作者: 安喜艳,Email: anxiyanzi@163.com E-mail:anxiyanzi@163.com

Treatment of wet age-related macular degeneration

AN Xi-yan,  SU Jiu-mei   

  1. Department of Ophthalmology,  The Third Central Hospital of Tianjin,  Tianjin 300170,  China
  • Received:2015-02-12 Online:2015-08-22 Published:2015-09-07
  • Contact: AN Xi-yan,Email:anxiyanzi@163.com E-mail:anxiyanzi@163.com

摘要:

年龄相关性黄斑变性(age-related macular degeneration,AMD)是50岁以上人群主要致盲眼病之一, 与干性AMD相比,湿性AMD病情发展更为迅速,是引起视力下降甚至丧失的主要原因。湿性AMD的治疗主要包括激光治疗、手术治疗、药物治疗、放射治疗及基因治疗。其中光动力疗法以及抗血管内皮生长因子药物的应用成为近年来湿性AMD治疗的热点,而抗血小板源性生长因子药物、放射治疗及基因治疗为湿性AMD的治疗提供了新思路。

Abstract:

Age-related macular degeneration (AMD) is one of the diseases resulting in blindness which happens among people over 50 years old in the world. Compared to dry AMD,  the development of wet AMD is more quickly and is the main cause of decreased visual acuity and vision loss . The treatments of wet AMD mainly include laser treatment,  surgery treatment,  drug treatment,   radiation therapy and gene therapy. Photodynamic therapy,  and anti-VEGF drugs became the hot spots in the treatment of wet AMD. Anti-platelet-derived growth factor (PDGF), radiation therapy and gene therapy provide the new thoughts for the treatment of wet AMD.