国际眼科纵览 ›› 2022, Vol. 46 ›› Issue (4): 378-384.doi: 10.3760/cma.j.issn.1673-5803.2022.04.017

• 综述 • 上一篇    

眼眶孤立性纤维瘤的临床特征及诊治进展

闫海涵   马建民   

  1. 首都医科大学附属北京同仁医院 北京同仁眼科中心 眼科学与视觉科学北京市重点实验室 100730

  • 收稿日期:2021-11-07 出版日期:2022-08-22 发布日期:2022-08-22
  • 通讯作者: 马建民,Email:jmma@sina.com
  • 基金资助:
    北京市医院管理中心登峰计划专项基金(DFL20190201);北京市自然科学基金(7222025)

Advances on orbital solitary fibrous tumor

Yan Haihan, Ma Jianmin   

  1. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing 100730, China
  • Received:2021-11-07 Online:2022-08-22 Published:2022-08-22
  • Contact: Ma Jianmin, Email: jmma@sina.com
  • Supported by:
    Beijing Hospitals Authority Ascent Plan (DFL20190201); Natural Science Foundation of Beijing (7222025)

摘要: 眼眶孤立性纤维瘤是一种来源于间叶组织的较为罕见肿瘤,可发生于眼眶各个部位,主要表现为眼眶部肿块和眼球突出。40~50岁是疾病高发年龄,男女发病率无差异。有一小部分患者肿瘤可复发和转移。本病临床和影像学多无显著特异性表现。其组织病理学形态改变广泛,有多种亚型,免疫组织化学染色具有较高的特异性。手术切除是治疗的主要方式,术后密切随诊至关重要。(国际眼科纵览,2022, 46:378-384)

关键词: 眼眶, 孤立性纤维瘤

Abstract: Orbital solitary fibrous tumor (SFT) is a rare tumor originating from perivascular multipotent mesenchyme and can occur in various parts of the orbit. Mass involving in the orbit and proptosis are the most common manifestations. The age of onset is 40-50 at most and there is no difference in incidence between men and women. A small percentage of orbital SFT patients may experience tumor recurrence and metastasis. The clinical and imaging findings of orbital SFT are mostly non-specific. The histopathological morphologic changes of orbital SFT are extensive and there are many subtypes. Immunohistochemical staining has high specificity. Surgical resection is the main treatment for orbital SFT, and close follow-up is very important. (Int Rev Ophthalmol, 2022, 46:  378-384)


Key words: orbital, solitary fibrous tumor