Abstract: Induced pluripotent stem cell (iPSC), a brand new cell with pluripotent differentiating ability, which was reconstructed and induced by 4 transcription factors and the genome of an adult cell. Kinds of diseases result in disfunctions of retina. The retinal regeneration will come true using the pluripotent differentiating ability of iPSCs. In the current, the hot spots of iPSC researches are as followings, the selections of donor adult cell/transcription factors/transcription carriers, mechanisms of the inducing process, ways of inducing iPSCs to differentiate to a particular layer of retina, and the transplantation of induced retinal pigmented epithelium and photoreceptor cells. However, there are still problems in the iPSC researches, such as the low differentiating efficiency, low survival rate after intraocular transplantation, and the unsecured safety in clinical utility, etc. And only by solving those problems can iPSC researches play a more important role in retinal regenerative medicine.