国际眼科纵览 ›› 2015, Vol. 39 ›› Issue (2): 84-89.doi: 10.3706/ cma. j. issn.1673/5803.2015.02.003

• 综述 • 上一篇    下一篇

人工晶状体材料及设计研究的进展

赵晶  万修华   

  1. 100005首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科研究所 眼科学与视觉科学北京市重点实验室
  • 收稿日期:2014-10-27 出版日期:2015-04-22 发布日期:2015-04-29
  • 通讯作者: 万修华,Email:xiuhuawan@126.com

The advances of the materials and designs of the intraocular lens

ZHAO Jing, WAN Xiu-hua   

  1. Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing 100005, China
  • Received:2014-10-27 Online:2015-04-22 Published:2015-04-29
  • Contact: WAN Xiu-hua,Email:xiuhuawan@126.com

摘要: 随着人口老龄化趋势的加重,白内障摘除联合人工晶状体(IOL)植入患者的数量逐步增加。IOL材料包括传统的聚甲基丙烯酸甲酯(PMMA)、硅胶、水凝胶和丙烯酸酯等。开发与使用稳定性、光学质量及安全性更好的新型IOL是提高患者术后视觉质量的需要。新型材料及设计的IOL包括注入式IOL、纳米材料IOL、羟乙基甲基丙烯酸酯(HEMA)材料IOL等。含HEMA的IOL疗效更确实、术后并发症更低;新型丙烯酸酯IOL独特的后缘尖锐化设计进一步降低术后并发症,提高IOL稳定性;注入式IOL实现了小切口手术、保留了晶状体正常的调节功能;纳米材料IOL提高了IOL生物相容性;新型黑色虹膜隔型IOL不仅使眼球美观,而且能够透过近红外线接受SLO、OCT等眼底检查。随着研究的深入与新材料的开发应用,这些IOL将很快问世,为白内障患者带来更多的福音。(国际眼科纵览, 2015, 39:   84-89)

Abstract: In the aging population, cataract extraction and intraocular lens (IOL) implantation  are gradually increased. IOL materials including traditional PMMA, silicone  hydrogel, acrylic  and so on. Development and use of  IOL with new design including better stability, optical quality and safety can improve the visual quality of cataract patient after surgery. New IOL including injectable IOL, nanocan materials’s IOL, hydroxyethyl methacrylate (HEMA) IOL and so on.  Postoperative complications of HEMA IOL is lower. The new acrylic IOL's unique sharp trailing edge can reduce complications and improve the stability of IOL. Injectable IOL makes smaller incision surgery as reality, as well as retains normal regulatory function of lens; nanomaterial’s IOL improves its biocompatibility. The new black iris diaphragm IOL looks better and allows to transmit near infrared light for SLO and OCT fundus examination. With further study and development of applications, these new IOLs will soon serve for cataract patients and bring better visual quality.   (Int Rev Ophthalmol, 2015, 39: 84-89)