国际眼科纵览 ›› 2025, Vol. 49 ›› Issue (3): 218-223.doi: 10. 3760/cma.j.cn115500-20241224-25310

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景深延长型人工晶状体研究进展

张晶雯  徐素  韩艺琳  王梓柏  张凤妍   

  1. 郑州大学第一附属医院眼科,郑州 450000
  • 收稿日期:2024-12-24 出版日期:2025-06-22 发布日期:2025-06-12
  • 通讯作者: 张凤妍,Email:Zhangfengyanx@aliyun.com

Research progress of extended depth-of-focus intraocular lens

Zhang Jingwen, Xu Su, Han Yilin, Wang Zibo, Zhang Fengyan   

  1. Department of Ophthalmology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China
  • Received:2024-12-24 Online:2025-06-22 Published:2025-06-12
  • Contact: Zhang Fengyan, Email: Zhangfengyanx@aliyun.com

摘要: 多焦点、三焦点和景深延长型(extended depth-of-focus,EDOF)人工晶状体(intraocular lens,IOL)因不同的光学设计可以满足患者多距离视力的需求。EDOF IOL创建一个延长的焦点以增强焦深达到连续视程,满足远中视力需求,减少眩光和光晕等光学干扰现象,但近视力略不足。将多焦点与EDOF技术相结合的多焦点EDOF IOL,根据不同的光学设计主要分为多焦折射型EDOF IOL、多焦衍射型IOL和折射衍射混合型多焦点EDOF IOL。这些IOL能够满足患者多距离视力的同时降低光学干扰现象,保持较高的视觉质量和对比敏感度,为白内障患者提供了更多的个性化IOL选择机会。而神经适应仍是多焦点 EDOF IOL的主要问题,未来需要进一步研究其机制及解决方案。


关键词: 白内障, 人工晶状体, 景深延长, 多焦点

Abstract: Multifocal, trifocal, and extended depth-of-focus (EDOF) intraocular lens (IOL) address patients' needs for multi-distance vision through distinct optical designs. EDOF IOL create an elongated focal point to enhance the depth of focus, achieving continuous vision range that meets intermediate and distance vision demands while reducing optical disturbances such as glare and halos, albeit with slightly compromised near vision. Multifocal EDOF IOL, which integrate multifocal and EDOF technologies, are primarily categorized into multifocal refractive EDOF IOL, multifocal diffractive IOL, and hybrid refractive-diffractive multifocal EDOF IOL based on their optical designs. These IOL enable multi-distance vision while minimizing optical interference, maintaining higher visual quality and contrast sensitivity, thereby offering cataract patients more personalized IOL options. However, neuroadaptation remains a significant challenge for multifocal EDOF IOL, necessitating further research into its mechanisms and solutions in the future.


Key words: Cataract, Intraocular lens, Extend depth-of-focus, Multi-focus