国际眼科纵览 ›› 2025, Vol. 49 ›› Issue (1): 32-38.doi: 10.3760/cma.j.cn115500-20240904-01006

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妊娠对脉络膜的影响

郝军生李忠恩2


  

  1. 1 莒县人民医院眼科,山东日照 276599; 2 山东中医药大学附属眼科医院,济南 250002
  • 收稿日期:2024-09-04 出版日期:2025-02-22 发布日期:2025-02-20
  • 通讯作者: 李忠恩,Email:lizhongenl@sina.com

Effects of pregnancy on the choroid

Hao Junsheng1,  Li Zhongen2   

  1. 1 Department of Ophthalmology, Juxian People's Hospital,Rizhao Shandong 276599,  China; 2 Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine,  Jinan 250002, China
  • Received:2024-09-04 Online:2025-02-22 Published:2025-02-20
  • Contact: Li Zhongen, Email: lizhongenl@sina.com

摘要: 妊娠是一个复杂的生理过程,由于血容量、外周血管阻力、激素等因素的变化,引起脉络膜厚度、脉络膜血管指数等指标的改变。这些脉络膜的变化是监测正常妊娠及预测妊娠并发症、合并症预后的无创生物标志物。OCT、吲哚青绿血管造影、超声多普勒等技术验证了脉络膜的形态、生理病理变化及临床生化检验指标揭示妊娠内环境变化与脉络膜的关系。妊娠也是脉络膜疾病发生及复发的影响因素之一。在妊娠对脉络膜的影响方面仍然存在争议,尚缺乏基础性研究,需要进一步研究来全面揭示妊娠期脉络膜的变化。 (国际眼科纵览,2025,  49:32-38)

关键词: 脉络膜, 妊娠, 妊娠期高血压, 妊娠期糖尿病

Abstract: Pregnancy is a complex physiological process,  changes in blood volume,  peripheral vascular resistance,  hormones,  and other factors cause changes in choroidal thickness,  choroidal vascular index,  and other markers,  and these choroidal changes are noninvasive biomarkers for monitoring normal pregnancy and predicting the prognosis of pregnancy complications and comorbidities.The morphology and physiological-pathological changes of the choroid have been verified by OCT,  indocyanine green angiography(ICGA),  ultrasound Doppler and other techniques. Clinical biochemical tests reveal the association of the changes in the internal environment of pregnancy affecting the choroid. Pregnancy is one of the factors that increase the incidence and recurrence of choroidal diseases. Controversial issues remain in understanding the effects of pregnancy on the choroid,  basic research is lacking,  and further studies are needed to fully reveal the choroidal changes during pregnancy. (Int Rev Ophthalmol,  2025,  49:  32-38)

Key words: choroid, pregnancy, hypertensive disorders of pregnancy, gestational diabetes mellitus