国际眼科纵览 ›› 2020, Vol. 44 ›› Issue (6): 413-418.doi: 10.3760/ cma.j.issn.1673-5803.2020.06.008

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眼底自发荧光检查在特发性黄斑裂孔诊断及视力预后判定中的应用

岳慧芳1  张蕴达2  张喜梅2   

  1. 1山西医科大学,太原 030001;  2山西省眼科医院视网膜科,太原 030002
  • 收稿日期:2020-03-22 出版日期:2020-12-22 发布日期:2020-12-29
  • 通讯作者: 张喜梅,Email: ximeizhang@sina.cn
  • 基金资助:
    山西省卫生健康委员会科技攻关计划项目(2011058);山西省应用基础研究项目青年科技研究基金(201801D221014)

Applications of fundus autofluorescence on diagnosis and visual prognosis assessment of idiopathic macular hole

Yue Huifang1,  Zhang Yunda2,  Zhang Ximei2   

  1. 1 Shanxi Medical University,  Taiyuan 030001,  China;  2 Department of Retina, Shanxi Eye Hospital,  Taiyuan 030002,  China
  • Received:2020-03-22 Online:2020-12-22 Published:2020-12-29
  • Contact: Zhang Ximei, Email: ximeizhang@sina.cn
  • Supported by:
    Technologies Research and Development Programs of Health Commission Foundation of Shanxi Province (2011058); Applied Basic Research Programs of Youth Technology Commission Foundation of Shanxi Province (201801D221014)

摘要: 眼底自发荧光(fundus autofluorescence,FAF)作为一种操作简便、非侵入性的成像技术,可通过判断视网膜中脂褐质及黑色素的变化,以高/低荧光呈现视网膜功能状况。特发性黄斑裂孔(idiopathic macular hole,IMH)的FAF图像表现为黄斑裂孔高荧光区及孔周围的环形低荧光。术后裂孔完全闭合,高荧光区消失,否则表现为持续高荧光状态。FAF图像表现与相干光断层扫描图像及视力有相关性。(国际眼科纵览,2020,  44:  413-418)


关键词: 眼底自发荧光, 特发性黄斑裂孔 ,

Abstract: Fundus autofluorescence (FAF) is a simple and non-invasive imaging modality. This technique based on the changes of lipofuscin and melanin within the retina,  gives insight into metabolic condition of retina. The FAF imaging of idiopathic macular hole (IMH) shows hyperautofluorescence corresponding to the hole area and surrounding hypoautofluorescent ring. The hyperautofluorescence can disappear or reduce due to a successful macular hole closure,  or can be persistent with an unclosed hole. FAF provides valuable information about diagnosis and follow-up of IMH,  combined with OCT has a great role both in vision prognosis,  understanding pathogenesis and anatomical and functional recovery. (Int Rev Ophthalmol,  2020,  44:  413-418)

Key words: fundus autofluorescence, idiopathic macular hole