International Review of Ophthalmology ›› 2026, Vol. 50 ›› Issue (3): 196-201.doi: 10.3760/cma.j.cn115500-20251014-26306

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Comparison of different platform  for refractive corneal lenticule extraction

Wang Shen1 , Jiang Yang2, Li Ying2   

  1. 1 Beijing Chaoju Eye Care, Beijing 100022, China; Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
  • Received:2025-10-14 Online:2026-06-22 Published:2026-06-22
  • Contact: Li Ying, Email: liyingpumch@126.com

Abstract: Keratorefractive lenticule extraction/refractive corneal lenticule extraction (KLEx/RCLE) is a type of laser corneal refractive surgery. In recent years, it has evolved from being represented solely by small incision lenticule extraction (SMILE) using a single femtosecond laser platform to a multi-platform approach, including the KLEx systems—SMILE (VisuMax 500), SMILE Pro (VISUMAX 800), SmartSight (SCHWIND ATOS), CLEAR (FEMTO LDV Z8), and SILK (ELITA). This review compares the similarities and differences among these five systems in terms of device design, surgical procedures, correction range, clinical outcomes, and complications. It aims to provide a reference for clinicians when selecting a KLEx system, while also identifying current gaps in evidence and future research directions. 

Key words: Refractive corneal lenticule extraction/ keratorefractive lenticule extraction, Myopia, Femtosecond laser