International Review of Ophthalmology

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Progress in research  of optic neuroprotection in glaucoma

ZHANG Yi,WU Ji-hong   

  1. Department of Ophthalmology, Experiment Research Center, Eye & ENT Hospital of Fudan University, Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, China
  • Received:2015-04-29 Online:2015-08-22 Published:2015-09-07
  • Contact: WU Ji-hong, Email: jihongwu@fudan.edu.cn E-mail:jihongwu@fudan.edu.cn

Abstract:

The development of therapeutic drugs and methods based on optic neuroprotection is a hot spot in glaucoma. Glaucomatous optic nerve damage involves multifactorial abnormity including neurotrophic factor deprivation, calcium overload and oxidative stresss. To carry out clinical translational researches on optic neuroprotection within a coherent framework are expected to provide novel effective therapeutic tools for glaucoma.