International Review of Ophthalmology ›› 2021, Vol. 45 ›› Issue (3): 188-193.doi: 10.3760/cma.j.issn.1673-5803.2021.03.003

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The research of neovascular glaucoma therapy

He Yuan1, Quan Zhuoya 1,2, He Beilei 1,2, Zhang Ruixue 1,2   

  1. 1Department of Ophthalmology, the Second Affiliated Hospital of Xi'an Medical University, Xi'an 710038, China; 2 Xi'an Medical University, Xi'an 710021, China

  • Received:2020-12-08 Online:2021-06-22 Published:2021-06-22
  • Contact: He Yuan, Email: openji7127@hotmail.com
  • Supported by:
    National Natural Science Foundation of China(81770929, 82070964); Shaanxi Provincial Department of Education in 2018 Serving Local Scientific Research Project Funding (18JC026); Shaanxi Provincial Department of Science and Technology Project (2019SF-162); Shaanxi Provincial Department of Education Project(19JK0758); Xi'an Science and Technology Bureau Project (2019114613YX001SF041-(2))

Abstract: Neovascular glaucoma (NVG) is a kind of refractory blinding eye disease which has poor therapeutic effect to drugs and surgery. Early applications of eye drops to lower the high intraocular pressure levels are effective in prevent any further deterioration of diseases. Panretinal photocoagulation can control the retinal ischemic primary disease and reduce the incidence of neovascularization in the anterior segment.Traditional filtration or shunt surgery is inevitable when peripheral anterior synechia formation and angle closure have occurred, and the results are unsatisfactory. In recent years, surgery combined with anti-vascular endothelial growth factor drugs has been considered as a novel method to improve the prognosis, but was not help to reduce intraocular pressure. Some ciliary body surgical seem to have good benefits on improving intraocular pressure. However, which treatment options are better for NVG patients deserve further investigation and exploration. (Int Rev Ophthalmol, 2021, 45: 188-193)

Key words: neovascular glaucoma, diabetic retinopathy, anti-vascular endothelial growth factor