International Review of Ophthalmology ›› 2023, Vol. 47 ›› Issue (6): 530-535.doi: 10.3760/cma.j.issn.1673-5803.2023.06.010

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Advances in the application of lens capsule grafting

Guo Zhaoqiong1,2, Yu Fangliang3   

  1. 1 The Third Clinical Medical College of Nanchang University,  Nanchang 330008, China; 2 Department of Ophthalmology, Nanchang Fisrt Hospital, Nachang 330008, China; 3 Eye Affiliated Hospital to Nanchang University, Nanchang 330008, China
  • Received:2023-05-07 Online:2023-12-22 Published:2023-12-22
  • Contact: Yu Fangliang, Email: 95518@qq.com
  • Supported by:
    Science and Technology Plan Project of Jiangxi Provincial Health Commission in 2023 (SKJP220229728)

Abstract: As a scraffold for good cell growth, the lens capsule is elastic, malleable, transparent, and available in cataract surgery, and is a simple and widely derived autologous material, which can be used as a graft in anti-glaucoma, treatment of refractory macular hole and corneal ulcer surgery. In trabeculectomy combined with cataract extraction and intraocular lens implantation, the autologous anterior capsule liner is padded under the scleral flap, which can not only play a good role in mechanical barrier, but also inhibit the occurrence of neovascularization and prevent the formation of cicatricial filter vesicles. Lens capsular flap transplantation promotes the proliferation and migration of Müller cells during macular hole surgical repair, thereby promoting macular hole healing; In vitro experiments, the lens capsule promotes corneal epithelial cell growth, adhesion and replacement of the Descemet's layer, maintaining corneal transparency. It may provide a new method for treating corneal ulcers.(Int Rev Ophthalmol, 2023, 47:  530-535)

Key words: lens capsule, implant, glaucoma, refractory macular hole, corneal ulcer