Abstract: Ultrasound cycloplasty (UCP) is a new non-invasive glaucoma treatment technology based on high-intensity focused ultrasound. UCP can effectively reduce intraocular pressure (IOP) in the treatment of various types of glaucoma such as primary glaucoma, neovascular glaucoma, traumatic glaucoma and other refractory glaucoma. For increased IOP again after UCP, it is also effective to administer repeated UCP treatment 3~6 months later, when the anterior chamber inflammation is under control. Meanwhile, UCP treatment can cause the changes on ocular structures and parameters, as well as related complications. Most of the complications, changes of ocular structures and parameters such as keratometry, conjunctival and scleral thickness, anterior chamber flare and pupil diameter were transient, usually recovered to preoperative level or subsided within 3~6 months after UCP. The change in anterior chamber depth have not been definitely reported after UCP. However, the scleral ciliary process angle was increased, and the ciliary body area was decreased after UCP. At the same time, further research is needed to clarify the changes and complications in the ocular posterior segment caused by UCP.  (Int Rev Ophthalmol, 2024, 48:  327-332)

Key words: ultrasound cycloplasty, glaucoma, ocular structure, ocular parameter