Abstract: Pregnancy is a complex physiological process,  changes in blood volume,  peripheral vascular resistance,  hormones,  and other factors cause changes in choroidal thickness,  choroidal vascular index,  and other markers,  and these choroidal changes are noninvasive biomarkers for monitoring normal pregnancy and predicting the prognosis of pregnancy complications and comorbidities.The morphology and physiological-pathological changes of the choroid have been verified by OCT,  indocyanine green angiography(ICGA),  ultrasound Doppler and other techniques. Clinical biochemical tests reveal the association of the changes in the internal environment of pregnancy affecting the choroid. Pregnancy is one of the factors that increase the incidence and recurrence of choroidal diseases. Controversial issues remain in understanding the effects of pregnancy on the choroid,  basic research is lacking,  and further studies are needed to fully reveal the choroidal changes during pregnancy. (Int Rev Ophthalmol,  2025,  49:  32-38)

Key words: choroid, pregnancy, hypertensive disorders of pregnancy, gestational diabetes mellitus