关键词: 黄斑, 视网膜厚度, 儿童, 近视

Abstract: Objective To assess the macular retinal thickness of children with low and moderate diopter myopia with spectral domain optical coherence tomography (SD-OCT). Design Cross-sectional study. Participants Myopia group included 54 children（108 eyes） at age of 7 to 12（9.80±1.44）,  with best-corrected distance visual acuity（BCDVA）≥1.0 and spherical equivalent（SE)（-6.00 D~-0.50 D）, without other ocular pathology. The normal control group included 58 children(116 eyes) （-0.50 D~0.50 D） at age of 7 to 12(9.78±1.58). Methods After comprehensive ophthalmic examination, optical coherence tomography (Cirrus HD-OCT, 512×218 cube scan pattern) was performed, and the difference between myopia group and control group was analyzed. Main Outcome Measures Central macular thickness(CMT), macular volume (MV), average macular thickness (AMT), average macular thickness of inner circle(I-AMT) and average macular thickness of outer circle(O-AMT). Results The difference of CMT between myopia group (239.7±18.1 μm)and control group (238.4±18.1 μm) was not significant （P=0.539). MV, AMT, I-AMT and O-AMT of myopia group were significantly thinner than control group(all P=0.000), and had a statistically significant association with SE (r=0.276~0.424，P=0.000~0.004). Conclusions CMT in low to moderate myopic eyes is not thinner than that of, emmetropic eyes, while the parafovea retinal thickness was thinner in myopic eyes. (Ophthalmol CHN, 2014, 23: 316-318)

Key words: macula, retinal thickness, children, myopia