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2004-2014年云南省西双版纳地区599例真菌性角膜炎临床分析

赵楠楠  王立涛  金靖  周清  罗平   

  1. 571000 海南医学院附属医院眼科(赵楠楠);666100云南省西双版纳州人民医院眼科(王立涛、金靖、周清、罗平)
  • 收稿日期:2015-04-08 出版日期:2017-01-25 发布日期:2017-01-20
  • 通讯作者: 赵楠楠,Email:65634536@qq.com
  • 基金资助:

    海南医学院附属医院青年培育基金项目(HYFYPY201603)

Clinical analysis of fungal keratitis in Xishuangbanna Autonomous Prefecture, Yunnan Province in 2004-2014

ZHAO Nan-nan1, WANG Li-tao2, JIN Jing2, ZHOU Qing2, LUO Ping2.   

  1. 1. Department of Ophthalmology, Affiliated Hospital of Hainan Medical College, 571000 Hainan, China; 2. The People's Hospital in Xishuangbanna, 666100 Yunnan, China
  • Received:2015-04-08 Online:2017-01-25 Published:2017-01-20
  • Contact: ZHAO Nan-nan, Email: 65634536@qq.com

摘要:

目的 了解2004-2014年云南省西双版纳地区真菌性角膜炎的人口学特征及病因。设计 回顾性病例系列。研究对象 2004年7月-2014年7月西双版纳州人民医院眼科599例真菌性角膜炎患者。方法 回顾分析患者的人口学特征、发病诱因、病原学特征及既往诊疗情况等。主要指标 人口学特征、病因及致病菌。结果 男女患病比为3:1,年龄35~65岁者占47.5%,农民为主(63.4%),雨季为高发季节(85.4%)。发病诱因中植物性外伤78.4%。未确诊前治疗使用糖皮质激素者占32.5%。致病菌中镰刀菌占37.8%、烟曲霉菌占32.7%。结论 男性中壮年农民雨季植物性外伤是西双版纳热带地区真菌性角膜炎主要患病危险因素。(眼科, 2017, 26: 49-51)

关键词:  , 真菌性角膜炎, 西双版纳热带地区

Abstract:

 Objective To analyze clinical features and pathogen of fungal keratitis in Xishuangbanna Autonomous Prefecture, Yunnan Province in 2004-2014. Design Retrospective case series. Participants 599 cases of fungal keratitis patients confirmed by Xishuangbanna Prefecture People's Hospital. Methods All cases were retrospectively reviewed for emographic characteristics, predisposing factors, etiological characteristics and previous treatments. Main Outcome Measures Emographic characteristics, etiology and pathogens. Results Prevalence ratio of male and female was 3:1, with major age range from 35 to 65 (47.5%).  Rural residents were 63.4%. There was a high incidence of fungal keratitis in wet season of Xishuangbanna area (85.4%). 78.4% cases were associated with plant-induced trauma. 32.5% patients had received glucocorticoid medication in early treatment. Fusarium (37.8%), aspergillus (32.7%) were the main pathogenic bacteria of fungal keratitis. Conclusions Young and middle-aged male farmers, plant-induced ocular trauma in rainy season are the main risk factors of fungal keratitis in Xishuangbanna area. (Ophthalmol CHN, 2017, 26: 49-51)

Key words:  fungal keratitis, Xishuangbanna area