眼科

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频域OCT测量黄斑区节细胞-内丛状层厚度在青光眼早期诊断中的应用

刘杏  徐晓宇   

  1. 510060 广州,中山大学中山眼科中心  眼科学国家重点实验室
  • 收稿日期:2016-01-11 出版日期:2016-01-25 发布日期:2016-01-28
  • 通讯作者: 刘杏,Email:liuxing@mail.sysu.edu.cn
  • 基金资助:

    广州市科技计划项目(2013J4500019)

The application of macular ganglion cell-inner plexiform layer thickness measured by spectral-domain optical coherence tomography in early glaucoma diagnosis 

LIU Xing, XU Xiao-yu.   

  1. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
  • Received:2016-01-11 Online:2016-01-25 Published:2016-01-28

摘要:

SD-OCT测量黄斑区节细胞-内丛状层(GCIPL)厚度有可能较视盘周围视网膜神经纤维层(RNFL)厚度、黄斑区节细胞复合体(GCC)更早地发现青光眼性结构损害。GCIPL在东方人群中鼻上方最厚、下方最薄。年龄及眼轴是影响GCIPL的重要因素。目前GCIPL厚度与RNFL厚度具有相似的临床诊断效能。其与视野、RNFL厚度、视盘参数相互整合,是提高青光眼早期检出率的关键。(眼科,2016,25:1-5)

关键词: 频域相干光断层扫描, 青光眼, 早期诊断, 节细胞-内丛状层

Abstract:

Macular ganglion cells-inner plexiform layer (GCIPL) thickness detected by SD-OCT may be a better method than peripapillary retinal nerve fiber layer (RNFL) thickness and macular ganglion cell complex (GCC) for earlier diagnosis of glaucomatous damage. GCIPL in  superonasal sector is the thickest while GCIPL in inferior sector is the thinnest in Asian population. Age and the axial length are important impact factors of GCIPL thickness. GCIPL thickness has similar glaucoma distinguishing performance with RNFL thickness. Mutual integration of visual field testing, GCIPL thickness, RNFL thickness and optic disc parameters is the key to enable early detection of glaucoma. (Ophthalmol CHN, 2016, 25: 1-5)

Key words: spectral-domain optical coherence tomography, glaucoma, early diagnosis, ganglion cell-inner plexiform layer