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弱视儿童治愈后双眼视知觉功能的观察

成娟娟  付晶  卢炜  褚航  阎丽   

  1. 100730 首都医科大学附属北京同仁医院 北京同仁眼科中心 眼科学与视觉科学北京市重点实验室(成娟娟、付晶、卢炜);512511 广州,国家医疗保健器具工程技术研究中心(褚航、阎丽)
     
  • 收稿日期:2016-05-22 出版日期:2017-09-25 发布日期:2017-09-28
  • 通讯作者: 卢炜,Email: yuancang@263.net

The binocular visual perception function after cure of amblyopia in children

CHENG Juan-juan, FU Jing, LU Wei, CHU Hang2,  YAN Li2   

  1. 1. Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; 2. National Engineering Research Center for Healthcare Devices, Guangzhou 512511, China
  • Received:2016-05-22 Online:2017-09-25 Published:2017-09-28
  • Contact: LU Wei, Email: yuancang@263.net

摘要:

目的 评估弱视儿童治愈后的双眼视知觉功能。设计 回顾性病例系列。 研究对象 75例屈光不正、屈光参差弱视治愈后儿童。方法  将患者按矫正视力分为轻度弱视(0.6~0.8)、中度弱视(0.2~0.5)和重度弱视(≤0.1)三组,比较分析三组弱视患儿治愈后双眼视知觉功能量化评估检测的状况。主要指标 知觉眼位差值与注视稳定性的波动差值、信噪比平衡点差值,对比度平衡点差值、随机点0阶立体视、1阶立体视、2阶立体视检测的通过百分比。结果 轻、中、重度弱视治愈后3°视标水平眼位均值依次为(22.63±18.94)、(31.96±32.70)、(46.86±31.70)像素,垂直眼位均值依次为(3.59±4.36)、(4.66±4.29)、(9.93±10.27)像素;1°视标水平眼位均值依次为(28.00±22.68)、(36.06±26.90)、(31.33±22.42)像素,垂直眼位均值依次为(4.74±5.15)、(5.69±5.04)、(7.80±12.03)像素。注视稳定性均值依次为(4.11±1.99)、(4.79±2.37)、(2.36±3.24)像素。静态信噪比的平衡点均值分别为(6.52±1.31)、(6.12±1.72)、(5.83±2.68)级,静态对比度的平衡点均值分别为(7.70±1.78)、(7.12± 2.29)、(6.53±3.05)级,静态信噪比差值分别为(1.48±1.48)、(1.63±1.45)、(2.20±1.89)级,静态对比度差值分别为(1.92±1.66)、(2.24±1.95)、(3.60±2.89)级。随机点0阶立体视均达到100"的儿童有53例(71%),1阶立体视68例(90%),2阶立体视通过73例(97%)。结论 弱视治愈后,双眼知觉眼位、双眼间的抑制程度及不同通道的立体视功能仍未达到正常水平,这种新的检查方法和结果分析对认识视力治愈后仍存在有视觉神经缺损提供了新的切入点。(眼科, 2017, 26: 299-302)

关键词: 弱视, 抑制, 立体视, 注视稳定, 知觉眼位

Abstract:

 Objective To evaluate the binocular visual perception function after cure of amblyopia in children. Design Retrospective case series. Paticipants 75 children with cured amblyopia due to ametropia and anisometropia. Methods The patients were divided into mild, moderate and severe amblyopia group according to the corrected visual acuity. Mild amblyopia was defined as corrected visual acuity varied from 0.6 to 0.8, moderate amblyopia with 0.2 to 0.5, severe amblyopia with less than 0.1. The quantitative assessment of binocular visual perception function in the three groups was compared. Main Outcome Measures Binocular perception eye position difference, binocular fixation difference, signal-to-noise ratio balance point difference, contrast balance difference, and the passing rate of random point 0-order, 1-order, 2-order stereopsis tests. Results After the participants with mild, medium and severe amblyopia were cured, we found that 3 °optotype horizontal eye level averaged at 22.63±18.94, 31.96±32.70, 46.86 ±31.70 pixels, respectively. The vertical eye level averaged at 3.59±4.36, 4.66±4.29, 9.93±10.27 pixels. 1 °optotype horizontal eye level averaged at 28.00±22.68, 36.06±26.90, 31.33±22.42 pixels, and the vertical eye level averaged at 4.74±5.15, 5.69±5.04, 7.80±12.03 pixels respectively. Binocular fixation stability averaged at 4.11±1.99, 4.79±2.37, 2.36±3.24 pixels for the three groups respectively. The static signal-to-noise ratio balance point averaged at 6.52±1.31, 6.12±1.72, 5.83±2.68 level. The balance point of static contrast averaged at 7.70±1.78 7.12±2.29 and 6.53±3.05 level. The static signal-to-noise ratio balance point difference was 1.48±1.48, 1.63±1.45 and 2.20±1.89 level and the balance point of static contrast difference was 1.92±1.66, 2.24±1.95 and 3.60±2.89 level respectively. In the random point 0-order stereoscopic test, 53 cases (71%) achieved 100 ", with 68 cases (90%) in 1-order stereoscopic test and 73 cases (97%) in 2-order stereopsis test. Conclusion After cure of amblyopia, the binocular perception, eye position, binocular inhibition and the stereopsis of different channels have not reached normal level. This new method of examination and analysis of the results of the visual recovery offers a new way to recognize the defects of visual system after cure of amblyopia. (Ophthalmol CHN, 2017, 26: 299-302)

Key words: amblyopia, inhibition, stereoscopic, binocular fixation, binocular perception eye position