眼科

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拟眼组织胞浆菌病

黄厚斌   

  1. 572013 海南三亚,解放军总医院海南医院眼科
  • 收稿日期:2018-11-06 出版日期:2019-09-25 发布日期:2019-09-24
  • 通讯作者: 黄厚斌,Email:huanghoubin@hotmail.com
  • 基金资助:
    海南省重点研发计划课题(ZDYF2018139);三亚市科技成果转化项目(2017CZ13)

Presumed ocular histoplasmosis syndrome

HUANG Hou-bin   

  1. Department of Ophthalmology, Hainan Hospital of PLA General Hospital, Sanya 572013, China
  • Received:2018-11-06 Online:2019-09-25 Published:2019-09-24
  • Contact: HUANG Hou-bin,Email:huanghoubin@hotmail.com

摘要: 随着对外层视网膜病变认识的深入,越来越多的眼科医师关注到拟眼组织胞浆菌病。组织胞浆菌可致组织胞浆菌病,拟眼组织胞浆菌病可能是组织胞浆菌病在眼部的表现。拟眼组织胞浆菌病的发病机理尚不清楚,临床表现为三联征:黄斑区或中周部孤立分散的萎缩性脉络膜视网膜瘢痕(组织斑或穿凿样病变)、视盘旁脉络膜视网膜萎缩、脉络膜新生血管或遗留的盘状瘢痕,以及一项阴性体征:不伴玻璃体和房水的炎性反应。需与其他的白点综合征疾病(多灶性脉络膜炎伴全葡萄膜炎、点状内层脉络膜病变、多发性一过性白点综合征、急性后极部多发性鳞状色素上皮病变、鸟枪弹样视网膜脉络膜病变、弥漫性视网膜下纤维化和匐行性脉络膜病变等)鉴别。治疗主要是针对脉络膜新生血管。(眼科, 2019, 28: 386-391)

关键词: 拟眼组织胞浆菌病, 组织胞浆菌病, 外层视网膜病变

Abstract: More and more ophthalmologists pay much attention to presumed ocular histoplasmosis syndrome (POHS), as with the graduallyin-depth understanding of outer retinal diseases. However, most eye doctors keep wondering the syndrome for the exotic disease is rare in China. In this article, the relationships among POHS, histoplasma and histoplasmosis are elucidated firstly, then the pathogenesis, clinical manifestations, differential diagnosis and treatments of POHS are summarized systematically. (Ophthalmol CHN, 2019, 28: 386-391)

Key words: presumed ocular histoplasmosis syndrome, histoplasma, outer retinal disease