倾斜对不同屈光度的景深延长型人工晶状体光学质量影响的实验研究

doi:10.13281/j.cnki.issn.1004-4469.2025.03.007

眼科 ›› 2025, Vol. 34 ›› Issue (3): 212-216.doi: 10.13281/j.cnki.issn.1004-4469.2025.03.007

倾斜对不同屈光度的景深延长型人工晶状体光学质量影响的实验研究

秦苏云¹ 廖萱¹ 兰长骏² 谢丽暄¹ 潘若琳¹ 谭青青¹ 黄欢¹ 王艳¹

¹川北医学院附属医院眼科川北医学院眼视光医学院，四川南充637000；²成都东区爱尔眼科医院成都高新区爱尔眼科研究所，成都610056

收稿日期:2024-10-25 出版日期:2025-05-25 发布日期:2025-05-25
通讯作者: 兰长骏，Email: eyelanchangjun@163.com
基金资助:
四川省医学科研课题（S21011）；成都市医学科研课题（2024268）；爱尔眼科医院集团临床研究所科研基金项目（AIG2306D01）

Experimental study on the influence of tilt on the optical quality of extended depth of focus intraocular lenses with different diopter

Qin Suyun¹, Liao Xuan¹, Lan Changjun², Xie Lixuan¹, Pan Ruolin¹, Tan Qingqing¹, Huang Huan¹, Wang Yan¹

¹ Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical; College Medical School of Ophthalmology & Optometry, North Sichuan Medical College, Nanchong Sichuan 637000, China; ²Chengdu Eastern Aier Eye Hospital; AIER Eye Institute in Chengdu High-tech Zone, Chengdu 610056, China

Received:2024-10-25 Online:2025-05-25 Published:2025-05-25
Contact: Lan Changjun, Email: eyelanchangjun@163.com
Supported by:
Medical Research Project of Sichuan Province (S21011); Medical Research Project of ChengduCity (2024268); Clinic Research Foundation of Aier Eye Hospital Group (AIG2306D01)

摘要/Abstract

摘要： 目的探讨倾斜对不同屈光度景深延长型人工晶状体（EDOF IOL）光学质量的影响。设计实验研究。研究对象不同屈光度TECNIS Symfony ZXR00 EDOF IOL。方法采用体外光学质量测试系统OptiSpheric IOL R&D评价+10 D、+20 D、+30 D的ZXR00，在 ISO-2模型角膜下测定IOL处于居中位置及倾斜3°、5°、7°、9°、11°时焦点处50 lp/mm的调制传递函数（MTF）值、MTF曲线和USAF分辨率测试图。主要指标 MTF值、MTF曲线和USAF分辨率测试图。结果倾斜3°时3种屈光度IOL的MTF值开始下降，倾斜5°、7°时MTF值继续下降，USAF图像显示倾斜7°内3种屈光度IOL保持相对较好的图像质量。倾斜9°时MTF值继续下降，+30 D屈光度IOL中焦点的USAF图像质量下降显著。倾斜至11°时，远焦点处+10 D、+20 D、+30 D ZXR00的50 lp/mm MTF值分别为0.336、0.293、0.287，中焦点处的MTF值分别为0.286、0.271、0.210，远、中焦点均表现为+10 D屈光度IOL光学质量最好，+30 D光学质量最差。MTF曲线显示远、中焦点均表现为IOL屈光度越低，光学质量下降幅度越小。发生倾斜后MTF曲线在高频区降幅更大，低频区降幅较小。结论倾斜对IOL的光学质量产生负面影响，倾斜7°内，3种屈光度IOL均有较好的抗倾斜能力。整体表现为IOL屈光度越低，抗倾斜能力越好。（眼科，2025，34： 212-216）

关键词: 人工晶状体, 景深延长, 体外测试, 倾斜

Abstract: Objective To evaluate the impact of tilt on the optical quality of EDOF IOL with different diopters. Design Experimental study. Participants TECNIS Symfony ZXR00 EDOF IOL with different diopters. Methods OptiSpheric IOL R&D was used to evaluate the optical quality of the +10 D, +20 D, and +30 D ZXR00. Under the ISO-2 model cornea conditions, the modulation transfer function (MTF) values at spatial frequencies of 50 lp/mm, MTF curves, and USAF resolution test charts were measured at each focal point of the IOL when the IOL was in the centered position and at tilt of 3°, 5°, 7°, 9°, and 11°. Main Outcome Measures MTF values, MTF curves, and USAF resolution test charts. Results With a tilt of 3°, the MTF values of all threeIOLs began to decline. And this decline continued at 5° and 7° tilt. The USAF images showed that all three IOLs maintained relatively good image quality within a tilt of 7°. With a tilt of 9°, the MTF values continued to decline, and the USAF image quality at intermediate focus of +30 D ZXR00 showed a significant decline. With a tilt of 11°, the 50 lp/mm MTF values for the +10 D, +20 D, and +30 D IOLs at the far focus were 0.336, 0.293, and 0.287, respectively, while at the intermediate focus, the values were 0.286, 0.271, and 0.210, respectively. Both the far and intermediate focus showed that the optical quality of the +10 D IOL was the best, while the +30 D IOL was the worst. At both far and intermediate focus, the MTF curves revealed that the lower the IOL diopter,the smaller decline in optical quality.After tilt, the MTF curves exhibited a greater decline in the high-frequency range and a smaller decline in the low-frequency range. Conclusion Tilt had a negative impact on the optical quality of the IOL. Within a tilt of 7°, the three diopter IOLs showed good resistance to tilt. Overall, the lower the IOL diopter, the better the tilt resistance. (Ophthalmol CHN, 2025, 34: 212-216)

Key words: intraocular lens, extended depth-of-focus, in vitro test, tilt

秦苏云廖萱兰长骏谢丽暄潘若琳谭青青黄欢王艳. 倾斜对不同屈光度的景深延长型人工晶状体光学质量影响的实验研究[J]. 眼科, 2025, 34(3): 212-216.

Qin Suyun, Liao Xuan, Lan Changjun, Xie Lixuan, Pan Ruolin, Tan Qingqing, Huang Huan, Wang Yan. Experimental study on the influence of tilt on the optical quality of extended depth of focus intraocular lenses with different diopter[J]. Ophthalmology in China, 2025, 34(3): 212-216.

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倾斜对不同屈光度的景深延长型人工晶状体光学质量影响的实验研究

Experimental study on the influence of tilt on the optical quality of extended depth of focus intraocular lenses with different diopter

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