眼内窥镜下睫状体光凝术治疗常规抗青光眼手术失败的外伤性青光眼的疗效分析

doi:10.13281/j.cnki.issn.1004-4469.2021.02.012

眼科 ›› 2021, Vol. 30 ›› Issue (2): 142-146.doi: 10.13281/j.cnki.issn.1004-4469.2021.02.012

眼内窥镜下睫状体光凝术治疗常规抗青光眼手术失败的外伤性青光眼的疗效分析

李琦琰¹ 陈小丽² 郑鹏飞¹ 唐炘¹

¹首都医科大学附属北京同仁医院北京同仁眼科中心眼科学与视觉科学北京市重点实验室 100730；²首都医科大学附属复兴医院眼科，北京100038

收稿日期:2021-02-09 出版日期:2021-03-25 发布日期:2021-03-26
通讯作者: 唐炘，Email：tangxin6398@sina.com
基金资助:
国家自然科学基金（81800827）

Treatment efficacy of endoscopic cyclophotocoagulation on post-traumatic refractory glaucoma

Li Qiyan¹, Chen Xiaoli², Zheng Pengfei¹, Tang Xin¹

¹ Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing 100730, China；² Department of Ophthalmology, Fuxing Hospital, Capital Medical University, Beijing 100038, China

Received:2021-02-09 Online:2021-03-25 Published:2021-03-26
Contact: Tang Xin, Email: tangxin6398@sina.com
Supported by:
National Natural Science Foundation of China（81800827）

摘要/Abstract

摘要： 目的探讨眼内窥镜下睫状体光凝术（ECP）治疗外伤性难治性青光眼的安全性和有效性。设计回顾性病例系列。研究对象 2013年5月至2020年5月北京同仁医院接受至少一次抗青光眼手术且术后眼压仍>21 mmHg的外伤性难治性青光眼患者24例（24眼）。方法采用ECP对所有患者进行治疗。术后平均随访（3.6±2.3）年（范围6个月~7年）。回顾患者术前、术后1天、术后1周及末次随访时的眼压、视力、降眼压药物使用、术后并发症情况。采用单因素重复测量方差分析（ANOVA）和配对t检验进行数据分析。主要指标 眼压、视力、降眼压药物使用情况。结果术前患者平均眼压（37.8±8.7） mmHg，末次随访时平均眼压为（21.9±6.9）mmHg（P<0.001），83.3%患者眼压≤21 mmHg。术前使用降眼压药物（2.75±0.79）种，末次随访时为（0.88±1.12）种（P＜0.001）。末次随访时87.5%患者视力不变或提高。术中及术后均无严重并发症发生。结论平均随访3.6年的结果显示，ECP治疗常规抗青光眼手术失败的外伤性青光眼的疗效良好。（眼科， 2021， 30： 142-146）

关键词: 外伤性青光眼, 难治性青光眼, 睫状体光凝, 内窥镜

Abstract: Objective To explore the safety and effectiveness of endoscopic cyclophotocoagulation (ECP) in the treatment of post-traumatic refractory glaucoma. Design Retrospective case series. Participants 24 eyes of 24 post-traumatic refractory glaucoma patients who previously had undergone anti-glaucoma surgeries at least 1 time at Beijing Tongren Hospital from May 2013 to May 2020. Methods ECP was used to treat all patients. Patients were followed up for at least 6 months and average 3.6±2.3 years (range 6 months to 7 years). Changes in intraocular pressure (IOP), visual acuity, the number of IOP-lowering drugs and complications were reviewed. The data were analyzed by ANOVA and paired t test. Main Outcome Measures IOP, visual acuity and the number of IOP-lowering drugs. Results The average pre-operation IOP was 37.8±8.7 mmHg. The IOP at last visit (21.9±6.9 mmHg) was significantly lower than that before the ECP (P<0.001), and the IOP was successfully controlled in 83.3%. The number of IOP-lowering drugs used before operation was 2.75±0.79, and it was 0.88±1.12 at the last follow-up after ECP. The difference was statistically significant (P＜0.001). The postoperative visual acuity remained unchanged or improved in 87.5% of the patients. There was no severe complication observed during or after ECP. The average follow-up of 3.6 years showed that ECP was effective in the treatment of traumatic refractory glaucoma. (Ophthalmol CHN, 2021, 30: 142-146)

Key words: traumatic glaucoma, refractory glaucoma, cyclophotocoagulation, endoscope

李琦琰陈小丽郑鹏飞唐炘. 眼内窥镜下睫状体光凝术治疗常规抗青光眼手术失败的外伤性青光眼的疗效分析[J]. 眼科, 2021, 30(2): 142-146.

Li Qiyan, Chen Xiaoli, Zheng Pengfei, Tang Xin. Treatment efficacy of endoscopic cyclophotocoagulation on post-traumatic refractory glaucoma[J]. Ophthalmology in China, 2021, 30(2): 142-146.

[1]	郑颖洁张一刘玉娟. 鼻内镜下手术治疗先天性泪囊囊肿的1年疗效观察[J]. 眼科, 2024, 33(1): 71-75.
[2]	杜秀娟王艺蓉沙芳孙璇毕宏生. 不同晶状体状态的硅油眼行Ahmed阀植入术的有效性及安全性[J]. 眼科, 2022, 31(5): 340-345.
[3]	陈霄雅王瑞雪丁文君卢亚楠. 内窥镜辅助与外路微导管引导的小梁切开术治疗原发性先天性青光眼的有效性和安全性对比[J]. 眼科, 2022, 31(5): 334-339.
[4]	郑颖洁张一范金鲁郑群. 鼻内窥镜下鼻腔泪囊吻合术治疗先天性泪点发育不全伴泪囊黏液囊肿的效果观察[J]. 眼科, 2022, 31(4): 286-291.
[5]	裴雪婷王书华. 基于爆破音的两种经巩膜睫状体光凝方案治疗难治性青光眼的疗效比较[J]. 眼科, 2020, 29(2): 147-151.
[6]	肖红霞叶汉元 . 两种不同型号的Ahmed阀治疗难治性青光眼的疗效评价[J]. 眼科, 2018, 27(5): 367-371.
[7]	陈琳王华唐炘. 眼内窥镜下睫状体光凝两种光凝范围对难治性青光眼的降眼压效果比较[J]. 眼科, 2018, 27(1): 31-35.
[8]	王兴存朱立强左文渊孟志强刘洋提同欣. 新型泪道内窥镜下微钻疏通联合人工鼻泪管置入治疗鼻泪管阻塞的效果[J]. 眼科, 2017, 26(6): 366-370.
[9]	周丹何雷庞秀琴. 玻璃体切除术中直视下睫状体光凝和经巩膜睫状体光凝治疗继发性青光眼的疗效比较[J]. 眼科, 2016, 25(5): 330-334.
[10]	张秀兰王家伟. 难治性青光眼的治疗策略[J]. 眼科, 2015, 24(3): 214-216.
[11]	崔燕辉于刚范金鲁张诚玥吴倩曹文红樊云葳. 经鼻鼻腔泪囊吻合术治疗儿童复杂性泪道阻塞的临床观察 [J]. 眼科, 2015, 24(3): 171-176.
[12]	王华, 唐炘, 孙霞, 王宁利. 超声乳化白内障摘除联合内窥镜指导下的房角分离术治疗闭角型青光眼合并白内障的初步疗效[J]. 眼科, 2014, 23(1): 18-21.
[13]	朱海景, 原慧萍. Ahmed FP-7青光眼引流阀治疗难治性青光眼的18个月效果[J]. 眼科, 2013, 22(4): 253-256.

眼内窥镜下睫状体光凝术治疗常规抗青光眼手术失败的外伤性青光眼的疗效分析

Treatment efficacy of endoscopic cyclophotocoagulation on post-traumatic refractory glaucoma

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 13

编辑推荐

Metrics

本文评价