眼科 ›› 2014, Vol. 23 ›› Issue (4): 243-246.doi: DOI:10.13281/j.cnki.issn.1004-4469.2014.04.007

• 论著 • 上一篇    下一篇

良性病变行眼眶内容剜除术37例临床分析

苏帆  肖利华     

  1. 100039  北京,武警总医院眼眶病研究所
  • 收稿日期:2014-03-27 出版日期:2014-07-25 发布日期:2014-07-22
  • 通讯作者: 肖利华,Email:xiaolihuawj@sina.com

Orbital exenteration for benign disease: 37 case series

SU Fan, XIAO Li-hua.   

  1.  The General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China
  • Received:2014-03-27 Online:2014-07-25 Published:2014-07-22
  • Contact: XIAO Li-hua, Email: xiaolihuawj@sina.com

摘要: 目的 分析良性病变行眶内容剜除术的适应证。设计 回顾性病例系列。研究对象 1999年11月至2010年8月武警总医院眼眶病研究所行眶内容剜除术的良性病变患者37例。方法 回顾性分析患者的病例资料。主要指标 眶内容剜除术原因、术式,病理诊断。结果 全眶内容剜除术35例(94.6%),后部眶内容剜除术2例(5.4%)。全眶内容剜除术联合放射性131I粒子植入术1例(2.7%)。病理诊断为炎性假瘤11例(29.7%),多形性腺瘤8例(21.6%),脑膜瘤6例(16.2%),韦格纳肉芽肿性病变4例(10.8%),血管外皮细胞瘤2例(5.4%),副神经节瘤、血管瘤、神经纤维瘤、纤维脂肪血管瘤、婴儿色素性神经外胚层肿瘤、眼眶结核各1例(2.7%)。眶内容剜除术原因:肿瘤切除术后复发或多次复发占86.5%,术眼视力无光感占54.1%,不可控制的疼痛占43.2%,肿瘤大或范围广占40.5%,长期用糖皮质激素或放疗但病情仍进展占27.0%。结论 对于眼眶良性病变因局部切除术后复发而困扰的患者,如伴有视力丧失,肿瘤大或范围广,不可控制的疼痛者,可行眶内容剜除术。该术式用于眼眶良性病变治疗时,可彻底清除病灶、最大限度降低复发率。(眼科,2014,23: 243-246)

关键词: 眼眶良性病变, 眼眶内容剜除术

Abstract: Objective  To analyze the indications of orbital exenteration for benign disease. Design  Retrospective case series. Participants Thirty-seven patients who had undergone orbital exenteration from November 1999 to August 2010 inclusive at Armed Police General Hospital. Methods Medical records of all patients were reviewed. Main Outcome Measures Type of orbital exenteration, pathologic diagnosis and reasons for orbital exenteration. Results The surgery types include total orbital exenteration(94.6%), subtotal orbital exenteration(5.4%), and total orbital exenteration with radioactive seeds(2.7%). Pathologic diagnosis were as the following: 11 cases (29.7%) of inflammatory pseudotumor, 8 cases (21.6%) of pleomorphic adenoma, 6 cases (16.2%)of meningioma, 4 cases (10.8%) of Wegener granuloma, 2 cases (5.4%) of hemangiopericytoma, and 1 case(2.7%) of paraganglioma, hemangioma, neurofibroma, fibrolipoangioma, baby pigmentosa tumors of neuroectoderm, and orbital osteoclasia, respectively. Reasons for orbital exenteration were as the following: recurrence or repeatedly recurrence (86.5%), no light perception of surgical eye( 54.1%), uncontrolled pain (43.2%), large or wide-spread tumor(40.5%), still advanced tumor with long time steroid therapy(27.0%). Conclusion The indications for orbital exenteration in management of benign orbital disease are recurrence or repeatedly recurrence of diseases with blindness, uncontrolled pain, large or wide-spread tumor. Orbital exenteration could be used to clear focal lesions completely and lower recurrence of orbital benign diseases significantly. (Ophthalmol CHN, 2014, 23: 243-246)

Key words: benign disease of orbital, orbital exenteration