Abstract:  Objective To observe the influence of posterior chamber phakic intraocular lens ( PC-PIOL) on the eye tissue and aqueous flow of the implanted eyes. Design Experimental study. Participant 20 New Zealand standard experiment rabbits (20 eyes). Methods 20 experiment rabbits were randomly divided into 2 groups, 10 rabbits each group, and the right eye in each group was observed PC-PIOL implanted only in eyes of experimental group. After inflammation caused by surgery was well controlled, tracer element was injected into posterior chamber of the experimental eye, and the time of its appearance in anterior chamber was recorded for the two groups. Then the anterior capsular membrane of right eyes in two groups was taken for examination with electron
microscope. Main Outcome Measures Proportion of eyes with tracer element appearing in anterior chamber corresponding time cost for tracer appearing, and the morphology of capsular cell. Results The tracer element appeared in anterior chamber in 4 eyes in experiment group, and 5 eyes in control group. The difference was not significant (χ²=0.639, P=0.412). The time of tracer appearance was (3.07±0.03) seconds in experiment group, and (2.42±0.08) seconds in control group (t=1.413，P=0.081). The cell morphology shows no unusual appearance between both groups. Conclusion The implantation of PC-PIOL did not induce the significant impact on capsular cell morphology short time after surgery, and did not obstruct acquous flow from posterior chamber to anterior chamber . (Ophthalmol CHN, 2015, 24: 97-99)

Key words: intraocular lens, posterior chamber, phakic eye, acquous, animal experimental