Abstract:

Objective To evaluate the effects of corneal higher-order aberrations of FEMTO LASIK and TransPRK for myopia patients. Design Prospective case control study. Participants One hundred thirty-one eyes of 73 Chinese patients with myopia and astigmatism whose spherical equivalent refraction ranged from -1.00 D to -6.75 D. Methods There were 68 eyes of 37 patients undergoing FEMTO LASIK and 63 eyes of 36 patients undergoing TransPRK using aberration free ablation with SCHWIND AMARIS excimer laser. Visual acuity, residual spherical equivalent, wavefront aberration were examined preoperatively, 1, 3 and 6 months postoperatively. Main Outcome Measures Visual acuity, manifest refraction, corneal higher-order aberrations including coma, spherical aberration and higher order aberration. Results On 1 month after surgery, the percent of postoperative UCVA better than or equal to preoperative BSCVA in FEMTO LASIK group was 75%, which was higher than in TransPRK group (47.62%) (P=0.001). On postoperative 3 and 6 months, the percent of postoperative UCVA better than or equal to preoperative BSCVA in FEMTO LASIK group was 86.76% and 91.18%, which were similar to that of TransPRK group (79.37% and 90.48% ) (P=0.26, 0.89). The residual spherical equivalent refraction in TransPRK group (0.13±0.35 D) was a little bit higher than that of FEMTO LASIK group (-0.02±0.41D). The coma of corneal in TransPRK group (0.25±0.10?m) was lower than that of FEMTO LASIK (0.30±0.17 ?m) on 1 month postoperatively (P=0.04). The coma in TransPRK group (0.28±0.10 ?m, 0.30±0.12 ?m) were similar in FEMTO LASIK (0.31±0.16 ?m, 0.35±0.11 ?m) on postoperative 3 and 6 months respectively (P=0.12 , 0.13). There were no significant differences between spherical and total higher-order aberrations on postoperative 1, 3 and 6 months. Conclusions Both FEMTO LASIK and TransPRK increase corneal higher-order aberrations. Coma was higher in FEMTO LASIK than in TransPRK group on postoperative 1 month. Corneal higher-order aberrations are comparable between two different surgeries on 3 and 6 months postoperatively. (Ophthalmol CHN, 2015, 24: 225-229)

Key words: myopia/surgery, excimer laser surgery, corneal aberration