Abstract:

Objective To compare two optical biometric instruments IOL master 500 and IOL master 700 for measuring the axial length(AL), keratometry(K) and anterior chamber depth(ACD) in silicone oil filled eyes. Design Prospective case series. Participants 34 cases (38 eyes) of silicone oil filled eyes were selected in September 2017 in Beijing Tongren Hospital Ophthalmology Inpatient Department. Methods The AL, K and ACD were measured using IOL master 500 and IOL master 700 successively. The results of two groups were compared using paired t test, reliability analysis, and MedCalc software was used to do the Bland-Altman analysis. Main Outcome Measures AL, mean keratometry(Km) and ACD. Results The AL detection rate of IOL master 500 and IOL master 700 were 89.5% (34/38) and 97.4% (37/38), respectively. There was no significant differences in AL, Km and ACD between IOL master 500 and IOL master 700. The AL was (25.05±3.37)mm and (25.03±3.35)mm (t=1.351, P=0.186) respectively. The Km was (43.42±3.10)D and (43.45±2.99)D (t=-0.393, P=0.697), and the ACD was (3.42±0.80)mm and (3.56±1.01)mm (t=-1.184, P=0.247), respectively. Reliability analysis of the two groups demonstrated AL(ICC＝1.000), Km(ICC＝0.996) and ACD(ICC＝0.857). The 95% consistency limits of Bland-Altman analysis showed AL(-0.1514 mm, 0.1920 mm), Km(-0.7723D, 0.7205D), ACD(-1.4057 mm, 1.1222 mm) and there were 2.94% (1/34), 8.82%(3/34) and 3.45%(1/29) of the points outside 95% consistency limit respectively. Conclusion There were no statistically significant differences in the axial length and mean keratometry of silicone oil filled eyes measured with IOL master 500 and IOL master 700. IOL master 700 had a higher detection rate of axial length in silicone oil filled eyes than IOL master 500 did. （Ophthalmol CHN，2018, 27： 349-352）

Key words: coherent optical biometrics, silicone oil filled eyes, axial length, keratometry, anterior chamber depth